Natural antimicrobial peptides from bacteria: characteristics and potential applications to fight against antibiotic resistance

Journal of Applied Microbiology
M HassanF Lotfipour

Abstract

Because of the emergence of antibiotic-resistant pathogens worldwide, a number of infectious diseases have become difficult to treat. This threatening situation is worsened by the fact that very limited progress has been made in developing new and potent antibiotics in recent years. However, a group of antimicrobials, the so-called bacteriocins, have been much studied lately because they hold a great potential in controlling antibiotic-resistant pathogens. Bacteriocins are small antimicrobial peptides (AMPs) produced by numerous bacteria. They often act toward species related to the producer with a very high potency (at pico- to nanomolar concentration) and specificity. The common mechanisms of killing by bacteriocins are destruction of target cells by pore formation and/or inhibition of cell wall synthesis. Several studies have revealed that bacteriocins display great potential in the medical sector as bacteriocinogenic probiotics and in the clinic as therapeutic agents. In this review, we discuss the emerging antibiotic resistance and strategies to control its dissemination, before we highlight the potential of AMPs from bacteria as a new genre of antimicrobial agents.

References

Nov 1, 1992·Journal of Bacteriology·R A Salomón, R N Farías
Nov 1, 1990·Journal of Bacteriology·M LaviñaF Moreno
Oct 1, 1967·The International Journal of Applied Radiation and Isotopes·J F BonteV A Stembridge
Feb 1, 1967·Journal of Bacteriology·E F Harrison, W A Zygmunt
Sep 1, 1984·Archives of Microbiology·V de Lorenzo
Mar 1, 1994·Applied and Environmental Microbiology·C M WilliamsonA J Lax
Jan 1, 1996·Biotechnology & Genetic Engineering Reviews·J A RamshawV Glattauer
Feb 4, 1998·Antimicrobial Agents and Chemotherapy·H BrötzH G Sahl
Sep 3, 1998·Applied and Environmental Microbiology·V G EijsinkI F Nes
Sep 17, 1998·The Journal of Antimicrobial Chemotherapy·B P GoldsteinR Novick
Feb 15, 2000·Research in Microbiology·M H Saier, I T Paulsen
Feb 2, 2002·Applied and Environmental Microbiology·A GravesenS Knøchel
Sep 1, 1995·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·David C.E. SpellerThomas R. Rogers
Mar 30, 2002·Nature Biotechnology·Arnold L Demain
Oct 24, 2002·Archives of Internal Medicine·C William WesterEnrique Martinez
Jan 25, 2003·Antimicrobial Agents and Chemotherapy·Scott WalshJames Mond
Feb 7, 2003·Applied and Environmental Microbiology·Marta DiazMercedes Maqueda
Mar 7, 2003·Applied and Environmental Microbiology·Robèr KempermanJan Kok
Apr 24, 2003·Antimicrobial Agents and Chemotherapy·John F Kokai-KunJames J Mond
May 24, 2003·Vaccine·Donata Medaglini, Arnd Hoeveler
Aug 15, 2003·Advances in Experimental Medicine and Biology·Jan Verhoef
Oct 1, 1964·Proceedings of the National Academy of Sciences of the United States of America·W KUNDIGS ROSEMAN
Oct 3, 2003·The Lancet Infectious Diseases·Delane Shingadia, Vas Novelli
Oct 25, 2003·Antimicrobial Agents and Chemotherapy·Julie A WuJohn F Kokai-Kun
Nov 19, 2003·Current Opinion in Infectious Diseases·John H Powers
Jan 19, 1952·Lancet·E M BAVINR FRIEDMANN

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Citations

Jan 9, 2013·Current Microbiology·Pennapa ManitchotpisitTimothy D Leathers
Feb 9, 2013·European Journal of Nutrition·C M C ChapmanI Rowland
Sep 10, 2013·Canadian Journal of Microbiology·Lauren M Petersen, Louis S Tisa
Nov 30, 2013·International Journal of Environmental Research and Public Health·Nerino AllocatiCarmine Di Ilio
Dec 12, 2012·International Journal of Molecular Sciences·Yanhua CuiHongyu Cui
Mar 19, 2014·The Journal of Antimicrobial Chemotherapy·Aman Preet SinghPraveen Rishi
Oct 11, 2014·Experimental Parasitology·Eglal I AmerHoda Mahrous
Jan 18, 2016·Biochimica Et Biophysica Acta·Panagiota K KyriakouYiannis N Kaznessis
Feb 23, 2013·Expert Opinion on Drug Discovery·Mario ZuccaDianella Savoia
Jan 23, 2016·Frontiers in Microbiology·Leon CantasTurgut Imir
Nov 3, 2015·Journal of Basic Microbiology·Samaneh Kazemi-ZaromiMahrokh Falahati-Rastegar
May 9, 2014·Molecular Microbiology·Paul D Cotter
Oct 9, 2015·Journal of Natural Products·Joana BarbosaSónia Mendo
Nov 14, 2014·Chemical Biology & Drug Design·Erin E GillRobert E W Hancock
Aug 8, 2015·Applied Biochemistry and Biotechnology·Tapasa Kumar SahooSriram Seshadri
Aug 5, 2014·Biotechnology Advances·Roberto MazzoliEnrica Pessione
Aug 6, 2015·Human Genomics·N V PuninaA F Topunov
Mar 21, 2015·Amino Acids·Lin WeiHailong Yang
Apr 22, 2015·Applied Microbiology and Biotechnology·Carine Nunes de AlmadaAnderson de Souza Sant'Ana
Dec 3, 2014·Plant Science : an International Journal of Experimental Plant Biology·Ravinder K Goyal, Autar K Mattoo
Mar 3, 2015·Chemistry & Biology·Olivia SoleckiBrice Felden
Oct 4, 2014·Frontiers in Microbiology·Alinne P de CastroOctávio L Franco
Jan 15, 2015·Applied Microbiology and Biotechnology·João Pinto da CostaRui Vitorino
Sep 6, 2014·Frontiers in Microbiology·Rafael R SilvaCesar A S Andrade
Nov 28, 2014·Applied Biochemistry and Biotechnology·Bassam AlkotainiAbdul Amir Hassan Kadhum
Jan 30, 2015·Canadian Journal of Microbiology·Chandra Datta SumiYoung Tae Hahm
Oct 22, 2014·Antimicrobial Agents and Chemotherapy·Rebeca MartínJuan E Suarez
May 6, 2016·Probiotics and Antimicrobial Proteins·Aabha GuptaMichael L Chikindas
May 11, 2016·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Jens Rolff, Paul Schmid-Hempel
Sep 3, 2016·Virulence·Preeti GaraiDipshikha Chakravortty
Jun 12, 2010·Meat Science·Wangang ZhangDong U Ahn
Oct 9, 2015·PLoS Biology·Richard William MeekLaura Jane Violet Piddock
Feb 3, 2016·Scientific Reports·Flavien PilletMarie-Pierre Rols
Apr 10, 2017·3 Biotech·Rajendra SinghPraveen Kumar Mehta
Apr 4, 2017·Expert Opinion on Biological Therapy·Josep M SierraMiguel Viñas

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