Natural Biomaterials as Instructive Engineered Microenvironments That Direct Cellular Function in Peripheral Nerve Tissue Engineering.

Frontiers in Bioengineering and Biotechnology
Rebecca PowellJames B Phillips

Abstract

Nerve tissue function and regeneration depend on precise and well-synchronised spatial and temporal control of biological, physical, and chemotactic cues, which are provided by cellular components and the surrounding extracellular matrix. Therefore, natural biomaterials currently used in peripheral nerve tissue engineering are selected on the basis that they can act as instructive extracellular microenvironments. Despite emerging knowledge regarding cell-matrix interactions, the exact mechanisms through which these biomaterials alter the behaviour of the host and implanted cells, including neurons, Schwann cells and immune cells, remain largely unclear. Here, we review some of the physical processes by which natural biomaterials mimic the function of the extracellular matrix and regulate cellular behaviour. We also highlight some representative cases of controllable cell microenvironments developed by combining cell biology and tissue engineering principles.

References

May 1, 1996·Anatomy and Embryology·S MatsudaT Fujiwara
Feb 25, 2000·Experimental Neurology·F J RodríguezX Navarro
Mar 4, 2000·Journal of Controlled Release : Official Journal of the Controlled Release Society·S E Sakiyama-Elbert, J A Hubbell
Aug 22, 2000·The Journal of the American Academy of Orthopaedic Surgeons·S K Lee, S W Wolfe
Oct 29, 2003·Current Opinion in Biotechnology·Tanyarut Boontheekul, David J Mooney
Nov 26, 2003·Experimental Neurology·Annie C LeeShelly E Sakiyama-Elbert
Feb 9, 2005·Journal of Biomaterials Science. Polymer Edition·Rebecca Kuntz Willits, Stacy L Skornia
May 26, 2005·Brain Research. Brain Research Reviews·Menachem Hanani
Jun 1, 2007·The Journal of Craniofacial Surgery·Soung-Min KimJong-Ho Lee
Jul 17, 2007·International Review of Cytology·Robert A Brown, James B Phillips
Aug 21, 2007·Journal of Biomaterials Science. Polymer Edition·Jan M BruderDiane Hoffman-Kim
Dec 29, 2007·Seminars in Immunology·James M AndersonDavid T Chang
Sep 4, 2008·Biotechnology and Bioengineering·Harini G SundararaghavanDavid I Shreiber
Oct 28, 2008·Tissue Engineering. Part a·Stephen F BadylakAnn M Stewart-Akers
Dec 19, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Emeline Van GoethemVéronique Le Cabec
Feb 9, 2010·Tissue Engineering. Part a·Shalu Suri, Christine E Schmidt
Apr 21, 2010·Nature Reviews. Neurology·Carla TaveggiaLawrence Wrabetz
Oct 19, 2010·Progress in Neurobiology·Ronald DeumensGary A Brook
Nov 3, 2010·Methods in Molecular Biology·Paul J KinghamGiorgio Terenghi
Feb 8, 2011·Biomaterials·Peter M CrapoStephen F Badylak
Mar 16, 2011·Journal of Neuroscience Methods·Ilary AllodiEsther Udina
Sep 3, 2011·Tissue Engineering. Part a·Alan J ManPeter Bannerman
Jul 24, 2012·Journal of Neuroinflammation·Elke YdensSophie Janssens
Aug 7, 2012·Genes & Cancer·Bryan L KrockM Celeste Simon
Nov 20, 2012·Biomaterials·Christopher J MedberryStephen F Badylak
Nov 23, 2012·The Journal of Bone and Joint Surgery. American Volume·Joo-Yup LeeAlexander Y Shin
Jan 11, 2013·Journal of Reconstructive Microsurgery·P Konofaos, J P Ver Halen
Jan 26, 2013·Journal of Neuroscience Methods·Mark StettnerBernd C Kieseier
May 28, 2013·ACS Chemical Neuroscience·Hossein HosseinkhaniKeng-Liang Ou
Jul 3, 2013·Tissue Engineering. Part B, Reviews·Melissa R Wrobel, Harini G Sundararaghavan
Dec 20, 2013·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Wendy MartensIvo Lambrichts
Jan 28, 2014·Biomaterials·Toral D ZaveriBenjamin G Keselowsky
May 6, 2014·Neuroscience Letters·Pietro G di SummaDaniel F Kalbermatten
May 9, 2014·The International Journal of Artificial Organs·Bill G X ZhangPeter F M Choong
Aug 12, 2014·BioMed Research International·Shimon Rochkind, Zvi Nevo
Nov 22, 2014·Nature Reviews. Molecular Cell Biology·Caroline BonnansZena Werb

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.