Natural calcium phosphates from fish bones and their potential biomedical applications

Materials Science & Engineering. C, Materials for Biological Applications
Pınar TerzioğluAyşe Kalemtaş

Abstract

The treatment and recovery of bio-wastes have raised considerable attention both from the environmental and economic point of view. Every year, a remarkable amount of fish processing by-products are generated and dumped as waste from all over the world. Fish bones can serve as a raw material for the production of high value-added compounds that can be used in various sectors including agrochemical, biomedical, food and pharmaceutical industries. The calcination of fish bones results in a single phase (hydroxyapatite) or bi-phasic (hydroxyapatite-tricalcium phosphate) bioceramics depending on the processing conditions as well as the content of the fish bones. This review summarizes the literature on the production of hydroxyapatite from fish bones and discusses their potential applications in biomedical field. The effect of processing conditions on the properties of final products including Ca/P ratio, crystal structure, particle shape, particle size and biological properties are presented in the light of X-ray diffraction, scanning electron microscopy, transmission electron microscopy, thermogravimetric-differential thermal analysis, bioactivity and biocompatibility investigations.

Citations

Aug 29, 2019·Chemical Society Reviews·Chunping XuRafael Luque
Jan 30, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Sana Ben-OthmanRajeev Bhat
Oct 31, 2020·Critical Reviews in Food Science and Nutrition·Seyed Fakhreddin HosseiniDavid Julian McClements
Nov 9, 2019·Marine Pollution Bulletin·Samaneh KarbalaeiAli Karami
Oct 30, 2020·Scientific Reports·Yangli XuLaijin Su
Jun 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Alessio AdamianoMichele Iafisco

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