PMID: 2106409Mar 1, 1990Paper

Natural course of treated pulmonary embolism. Evaluation by perfusion lung scintigraphy, gas exchange, and chest roentgenogram

Chest
R PredilettoC Giuntini

Abstract

Perfusion lung scintigrams, pulmonary gas exchange data, and chest roentgenograms were obtained in 33 patients during acute embolism and over the following six months in order to assess their clinical usefulness in monitoring the effect of therapy. To this purpose, the measurement of pulmonary gas exchange and the presence of chest x-ray findings were compared with perfusion lung scintigraphic abnormalities both at diagnosis and after 7, 30, and 180 days during treatment. More than 50 percent of the pulmonary arterial tree was obstructed at diagnosis, and a large part of perfusion recovery was complete within the first month. All of the gas exchange parameters were abnormal at diagnosis, and the rate of their improvement was related to that of perfusion recovery. Interestingly, PaO2st (ie, PaO2 corrected for hyperventilation) and VE tended to return to normal during the first month as a consequence of the progressive recovery of perfusion, whereas oxygen and carbon dioxide gradients and physiologic dead space showed the persistence of some abnormalities six months after diagnosis. Significant correlations were observed between the number of ULSs evaluated on the perfusion lung scintigram (and considered an index of the severity...Continue Reading

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Citations

Jan 28, 2009·European Journal of Nuclear Medicine and Molecular Imaging·John H ReidUNKNOWN International Atomic Energy Agency Consultants' Group
Sep 25, 1998·Journal of Internal Medicine·K OlssonP Wollmer
Jul 4, 2002·Thorax·M C ZoiaUNKNOWN Pavia Thromboendarterectomy Group
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