Natural cycle frozen-thawed embryo transfer in young women with regular menstrual cycles increases the live-birth rates compared with hormone replacement treatment: a retrospective cohort study

Fertility and Sterility
Xitong LiuJuanzi Shi

Abstract

To determine the optimal endometrial preparation protocols of frozen-thawed embryo transfer (FET) in young women with regular menstrual cycles. Retrospective cohort study. Public fertility center. Infertile women with regular menstrual cycles undergoing FET. Natural cycle (NC) treatment for patients with proven ovulation in previous cycles or who refused medication (n = 308), or hormone treatment (HT) for patients who could not be frequently monitored (n = 1,538). Live-birth rates. The live-birth rates were 61.73% in the NC group and 55.11% in the HT group. The effect size of the endometrial preparation on live-birth rates was evaluated in prespecified and exploratory subgroups in each subgroup, and multivariable logistic regression analysis was used to determine which variables could be independently associated with the live-birth rate. The HT patients had a lower chance of live birth in all subgroups: endometrial thickness on the day of progesterone administration, triple-line endometrial pattern, female age at embryo transfer, fertilization type, and protocol in the fresh cycle. Multivariable analysis showed NC to be associated with an increased likelihood of live birth compared with HT. Natural cycle treatment has a higher ...Continue Reading

References

Apr 24, 2007·Journal of Assisted Reproduction and Genetics·Vadim MorozovSteven Brenner
Nov 6, 2007·Fertility and Sterility·Kalliopi E LoutradiBasil C Tarlatzis
Jul 30, 2010·The Journal of Obstetrics and Gynaecology Research·Yong Jin KimShin Yong Moon
Mar 7, 2012·Journal of Assisted Reproduction and Genetics·Katharina HanckeJürgen M Weiss
Jul 16, 2014·The International Journal of Developmental Biology·Rani FritzD Randall Armant
Aug 8, 2015·Biology of Reproduction·Shivali PatelDebra F Skafar
Mar 15, 2016·Journal of Assisted Reproduction and Genetics·Raoul OrvietoJigal Haas
Aug 3, 2016·Journal of Assisted Reproduction and Genetics·Wan-Tinn TehPeter Rogers
Nov 9, 2017·Human Reproduction·Fernando Zegers-HochschildSheryl van der Poel
Apr 18, 2018·Turkish Journal of Obstetrics and Gynecology·Marzieh Agha-HosseiniMahshad Khodarahmian

❮ Previous
Next ❯

Citations

Jun 18, 2020·Frontiers in Endocrinology·Paolo Emanuele Levi SettiPasquale Patrizio
Jun 26, 2021·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Ruma SatwikMohinder Kochhar
Jul 27, 2021·Frontiers in Endocrinology·Sezcan MumusogluHakan Yarali
Sep 28, 2021·Frontiers in Medicine·Freya WaschkiesFrauke von Versen-Höynck

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.