Natural History and Consequences of Nonunion in Mandibular and Maxillary Free Flaps

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
Brian SwendseidJoseph M Curry

Abstract

To describe the natural history of bone segment union in head and neck free flap procedures and detail the association of poor segment union with postoperative complications. Case series with chart review. Single tertiary care referral center. Patients with mandibular or maxillary defects reconstructed with osseous or osteocutaneous free flaps were analyzed (n = 104). Postoperative computed tomography or positron emission tomography/computed tomography scans were reviewed for signs of osseointegration and nonunion. Postoperative wound complications were correlated with imaging findings. Thirty-seven percent of appositions had partial union on nonunion. Appositions between osteotomized free flap segments form complete unions at a higher rate than appositions with native bone (65% vs 53%, P = .0006). If an apposition shows a gap of ≥1 mm, the chances of failing to form a complete union are greatly increated (79% vs 8%, P = .0009). Radiographic nonunion was associated with an increased likelihood of postoperative wound complications (40% vs 19%, P = .025) and in most cases was present before development of complications. Radiographic evidence of partial union or nonunion of free flap osseous segments greatly exceeds reported rates...Continue Reading

References

Oct 23, 2008·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Pushkar Mehra, Haitham Murad
Dec 20, 2011·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Larissa SweenyEben L Rosenthal
Apr 5, 2012·Microsurgery·Catherine F SinclairEben L Rosenthal
Apr 26, 2013·Journal of Reconstructive Microsurgery·Tuija M Yla-KotolaStefan O P Hofer
Jun 4, 2014·The Laryngoscope·Tyler S WeaverMark K Wax
Mar 31, 2015·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Alberto GrammaticaPiero Nicolai
Oct 5, 2016·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Kun HwangHun Kim
Jan 8, 2017·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Adam P FaginDaniel Petrisor
Mar 21, 2017·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Candace A MitchellAdam Luginbuhl
Jun 18, 2017·Spine Deformity·Matthew StreetJohn Ferguson
Aug 9, 2017·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Maria H J HollanderJurjen Schortinghuis
Jul 1, 2017·Spine Deformity·Matthew StreetJohn Ferguson

❮ Previous
Next ❯

Citations

Feb 24, 2021·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Larissa SweenyMark K Wax

❮ Previous
Next ❯

Software Mentioned

IntelliSpace PACS Enterprise

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

British Medical Journal
A S Bankart
The Journal of Bone and Joint Surgery. American Volume
R D RAYK O FETROW
The Journal of the American Osteopathic Association
J P LEONARD, W L BROTT
© 2022 Meta ULC. All rights reserved