Natural history and symptomatology of Helicobacter pylori in childhood and factors determining the epidemiology of infection

Journal of Pediatric Gastroenterology and Nutrition
Ahmet OzenEnder Pehlivanoglu

Abstract

High seroprevalence rates for Helicobacter pylori have been reported in developing countries, yet few studies exist determining the pattern of change in the epidemiology of H. pylori infection in children. The knowledge of acquisition and loss rates of H. pylori and the relevance to the sociodemographic properties and the symptomatology of infection may provide clues for lifestyle changes that might protect children from infection, and also, it may provide rationale for eradication, screening, and protection policies. Our aim was to conduct a prospective study to elucidate the outcome, rate of acquisition, and loss of H. pylori infection in a population of healthy children. This study is based on follow-up of 327 healthy Turkish children aged 3 to 12 years. The follow-up was conducted 6 years after the baseline examination. Helicobacter pylori status was determined by C-urea breath test. Children were investigated for sociodemographic variables and several symptoms. Data from 136 (41%) of 327 children were available. The prevalence of infection increased from 52.9% to 56.6%, mainly increasing in children younger than 10 years. The incidence of H. pylori infection among previously uninfected children was 14%, and the loss rate o...Continue Reading

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Citations

Oct 21, 2006·Current Opinion in Gastroenterology·Gayle Horvitz, Benjamin D Gold
Jan 10, 2012·Journal of Pediatric Gastroenterology and Nutrition·Ximena DuquePelayo Correa
Jul 3, 2008·Digestive Diseases and Sciences·Engin TutarEnder Pehlivanoglu
Jan 30, 2010·Digestive Diseases and Sciences·Mahir GulcanAyca Vitrinel
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