Natural history of bilateral mild isolated antenatal hydronephrosis conservatively managed.

Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
Laura Fernanda Alconcher, María Marcela Tombesi

Abstract

The purpose of this study was to assess the prevalence and outcome of newborns with bilateral mild isolated antenatal hydronephrosis managed with neither antibiotic prophylaxis nor voiding cystourethrography (VCUG). Inclusion criteria were ultrasonographic evidence of an anterior-posterior pelvic diameter (APPD) of 5-15 mm at the third trimester of gestation and on the first postnatal ultrasound sonogram. Exclusion criteria were an APPD >15 mm, calyectasis, hydroureteronephrosis, or renal or bladder abnormalities. Ultrasound follow-up was performed. Parents were familiarized with the signs of urinary tract infection (UTI). If UTI was confirmed, VCUG was performed. The outcome was assessed as intrauterine resolution of hydronephrosis, total or partial resolution, stability, or progression. Hydronephrosis was bilateral in 98 of the 236 newborns (196 hydronephrotic kidneys) with mild isolated antenatal hydronephrosis enrolled in this study. Nine patients had UTI, and none showed reflux. After a mean follow-up of 15 months, 74 kidneys showed intrauterine resolution (38%), 82 (42%) showed total resolution, 13 showed partial resolution, 24 were stable, and 3 showed progression. Bilateral cases represented 42% of mild isolated antenat...Continue Reading

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Citations

Mar 12, 2013·Indian Pediatrics·Aditi SinhaUNKNOWN Indian Society of Pediatric Nephrology
May 30, 2013·Indian Journal of Nephrology·A SinhaI Agarwal
Sep 5, 2014·Journal of Pediatric Urology·Ramiro J Madden-FuentesSherry S Ross
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Mar 19, 2019·International Journal of Urology : Official Journal of the Japanese Urological Association·Eriko KohataKazunari Kaneko
Mar 12, 2020·Investigative and Clinical Urology·Pornpimol Rianthavorn, Suratsawadi Phithaklimnuwong
Mar 20, 2019·European Journal of Pediatrics·A Midhat Elmaci, M İrfan Dönmez
Mar 13, 2020·International Journal of Urology : Official Journal of the Japanese Urological Association·Miyuki KohnoMasayuki Kubota
Jun 25, 2020·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Maria HertheliusKarl-Johan Lidefelt
May 23, 2020·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Spyros BakalisDivyesh Desai

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