Natural history of coexistent mitral regurgitation after aortic valve replacement

The Journal of Thoracic and Cardiovascular Surgery
Sarah A SchubertRavi K Ghanta

Abstract

The long-term evolution of coexistent mitral regurgitation (MR) after aortic valve replacement (AVR) for aortic stenosis remains poorly defined. Prior studies have demonstrated that acute improvement in MR after AVR is modest, and more aggressive approaches have been advocated. This study examines the evolution of MR after AVR and identifies prognostic indicators for MR improvement. We retrospectively evaluated demographic and echocardiographic data of 423 patients who underwent primary isolated AVR for aortic stenosis with coexistent mild (n = 314) or moderate (n = 109) MR at our institution, from 2004 to 2013. For each patient, preoperative and postoperative MR was extracted from 903 echocardiograms and graded on a 0 to 4+ scale. Hierarchic linear models were used to estimate postoperative residual MR over a 5-year follow-up period. Patients were then stratified by improvement in MR, and preoperative risk factors and survival were compared between groups. Cox proportional hazards regression was used to assess the association between survival and preoperative and postoperative MR. The overall acute reduction in MR was -0.23 degrees per patient. Patients with moderate MR had a -0.53 degree reduction in MR, whereas patients with...Continue Reading

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Citations

Sep 22, 2016·The Journal of Thoracic and Cardiovascular Surgery·Masashi Komeda
Oct 3, 2018·Journal of Cardiac Surgery·Garrett N CoyanArman Kilic
Sep 15, 2019·Current Cardiology Reports·Rodney De PalmaMagnus Settergren
Jul 5, 2018·Frontiers in Cardiovascular Medicine·Barbara E StähliAlexander Lauten
May 1, 2020·International Heart Journal·Anne-Sophie SillesenPeter Godsk Jørgensen
May 23, 2017·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Fabio BariliLorenzo Menicanti
Jan 14, 2021·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Giorgio A MedrandaStephen J Green
Dec 29, 2020·Seminars in Cardiothoracic and Vascular Anesthesia·Nicolas KumarManoj H Iyer
Sep 19, 2021·The Annals of Thoracic Surgery·Alina NicoaraMiklos D Kertai

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