PMID: 7538093Jan 1, 1995Paper

Natural history of HCV seropositive cases found in health screening

[Hokkaido igaku zasshi] The Hokkaido journal of medical science
M Fukui

Abstract

In order to elucidate causative factors in HCV infection and natural history of HCV seropositive cases, examinees of adult health screening in two rural districts near Asahikawa (Groups A and B) were tested for HCV antibody and the clinical data of the HCV seropositive cases were retrospectively followed up. The examinees who showed cut-off index not less than 2.0 in C100-3 antibody test were taken as HCV seropositive cases. HCV seropositive rate was 5.1% for Group A, compared with 2.7% for Group B. HCV related factors were examined between HCV seropositive cases and age/sex-matched controls in the same group. As a result, blood transfusion and operation histories proved to be responsible for HCV seroreactivity in both Groups A and B. Although no significant difference was noted in blood transfusion and operation histories between Groups A and B, the rates with past history of liver disease, HBV exposure, and advanced age above 60 were significantly higher for Group A, suggesting HCV related factors other than blood transfusion and operation to be regionally different. Majority of HCV seropositive cases (79.2%) were ALT-normal, but 42.5% and 32.5% of this group showed ZTT- and ADA-abnormality, compared with 6.5 and 10.9% of the...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.