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Natural products to drugs: daptomycin and related lipopeptide antibiotics

Natural Product Reports

Nov 29, 2005

Richard H BaltzStephen K Wrigley

Abstract

Daptomycin (Cubicin) is a lipopeptide antibiotic approved in the USA in 2003 for the treatment of skin and skin structure infections caused by Gram-positive pathogens. It is a member of the 10-membered cyclic lipopeptide family of antibiotics that includes A54145, calcium-dependent anti...read more

Mentioned in this Paper

Calcium [EPC]
Derivatives
Calcium
Antibiotic throat preparations
Natural Products
Cubicin
Antifungal Antibiotics, Topical
Amphomycin
Daptomycin
Etiology
144
1
Paper Details
References
  • References144
  • Citations106
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  • References144
  • Citations106
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Natural products to drugs: daptomycin and related lipopeptide antibiotics

Natural Product Reports

Nov 29, 2005

Richard H BaltzStephen K Wrigley

PMID: 16311632

DOI: 10.1039/b416648p

Abstract

Daptomycin (Cubicin) is a lipopeptide antibiotic approved in the USA in 2003 for the treatment of skin and skin structure infections caused by Gram-positive pathogens. It is a member of the 10-membered cyclic lipopeptide family of antibiotics that includes A54145, calcium-dependent anti...read more

Mentioned in this Paper

Calcium [EPC]
Derivatives
Calcium
Antibiotic throat preparations
Natural Products
Cubicin
Antifungal Antibiotics, Topical
Amphomycin
Daptomycin
Etiology
144
1

Similar Papers Found In These Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.

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Current Topics in Medicinal Chemistry

Biosynthesis and genetic engineering of lipopeptide antibiotics related to daptomycin

Current Topics in Medicinal ChemistryMay 14, 2008
Richard H Baltz
Paper Details
References
  • References144
  • Citations106
12345...
  • References144
  • Citations106
12345...
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