Natural skin-whitening compounds for the treatment of melanogenesis (Review)

Experimental and Therapeutic Medicine
Wenhui QianHua Su

Abstract

Melanogenesis is the process for the production of melanin, which is the primary cause of human skin pigmentation. Skin-whitening agents are commercially available for those who wish to have a lighter skin complexions. To date, although numerous natural compounds have been proposed to alleviate hyperpigmentation, insufficient attention has been focused on potential natural skin-whitening agents and their mechanism of action from the perspective of compound classification. In the present article, the synthetic process of melanogenesis and associated core signaling pathways are summarized. An overview of the list of natural skin-lightening agents, along with their compound classifications, is also presented, where their efficacy based on their respective mechanisms of action on melanogenesis is discussed.

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Citations

Aug 30, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Dae Kil JangHee Min Yoo
Nov 19, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Joanna NawrotGerard Nowak
Mar 28, 2021·The Science of the Total Environment·Ayesha AslamMohammed Zwawi
Apr 4, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ji-Hyun LeeDae-Ki Kim
May 1, 2021·International Journal of Molecular Sciences·Seo-Mi-Gon Jeong, Tae-Jin Yoon
Jun 3, 2021·International Journal of Molecular Sciences·Il-Sup KimCheorl-Ho Kim
Jul 3, 2021·International Journal of Molecular Sciences·Ammar Akram KamarudinNorhaizan Mohd Esa
Jul 3, 2021·International Journal of Molecular Sciences·Kyuri KimKyung-Min Lim
Aug 21, 2021·Journal of Cosmetic Dermatology·Leong-Perng ChanChia-Hua Liang

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