Natural variation in the promoter of OsHMA3 contributes to differential grain cadmium accumulation between Indica and Japonica rice

Journal of Integrative Plant Biology
Chao-Lei LiuQian Qian

Abstract

Rice is a major source of cadmium (Cd) intake for Asian people. Indica rice usually accumulates more Cd in shoots and grains than Japonica rice. However, underlying genetic bases for differential Cd accumulation between Indica and Japonica rice are still unknown. In this study, we cloned a quantitative trait locus (QTL) grain Cd concentration on chromosome 7 (GCC7) responsible for differential grain Cd accumulation between two rice varieties by performing QTL analysis and map-based cloning. We found that the two GCC7 alleles, GCC7PA64s and GCC793-11 , had different promoter activity of OsHMA3, leading to different OsHMA3 expression and different shoot and grain Cd concentrations. By analyzing the distribution of different haplotypes of GCC7 among diverse rice accessions, we discovered that the high and low Cd accumulation alleles, namely GCC793-11 and GCC7PA64s , were preferentially distributed in Indica and Japonica rice, respectively. We further showed that the GCC7PA64s allele can be used to replace the GCC793-11 allele in the super cultivar 93-11 to reduce grain Cd concentration without adverse effect on agronomic traits. Our results thus reveal that the QTL GCC7 with sequence variation in the OsHMA3 promoter is an importan...Continue Reading

References

Feb 15, 2000·International Archives of Occupational and Environmental Health·T WatanabeM Ikeda
Jul 18, 2002·Trends in Plant Science·Stephan ClemensUte Krämer
Apr 3, 2003·The Science of the Total Environment·Teruomi TsukaharaMasayuki Ikeda
Jul 21, 2004·The Science of the Total Environment·T WatanabeM Ikeda
Aug 16, 2006·Biochimica Et Biophysica Acta·Yaniv Nevo, Nathan Nelson
May 5, 2009·Toxicology and Applied Pharmacology·Lars Järup, Agneta Akesson
Jun 10, 2009·Bioinformatics·Heng LiUNKNOWN 1000 Genome Project Data Processing Subgroup
Dec 30, 2009·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Kouichi TezukaHiromori Akagi
Feb 4, 2010·Environmental Health Perspectives·Soisungwan SatarugDonald A Sens
Jun 3, 2010·Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine·Tim S NawrotJaco Vangronsveld
Sep 9, 2010·Proceedings of the National Academy of Sciences of the United States of America·Daisei UenoJian Feng Ma
Dec 4, 2010·Journal of Experimental Botany·Daisei UenoJian Feng Ma
Nov 30, 2011·Plant & Cell Physiology·Namiko Satoh-NagasawaHiromori Akagi
Dec 14, 2011·Proceedings of the National Academy of Sciences of the United States of America·Shimpei UraguchiToru Fujiwara
May 3, 2012·Plant, Cell & Environment·Ryuichi TakahashiHiromi Nakanishi
May 17, 2012·The Plant Cell·Akimasa SasakiJian Feng Ma
Sep 18, 2012·Trends in Plant Science·Stephan ClemensNathalie Verbruggen
Nov 8, 2012·Proceedings of the National Academy of Sciences of the United States of America·Satoru IshikawaHiromi Nakanishi
Apr 17, 2013·Current Opinion in Plant Biology·Shimpei Uraguchi, Toru Fujiwara
Aug 14, 2013·Proceedings of the National Academy of Sciences of the United States of America·Zhen-Yu GaoQian Qian
Apr 4, 2014·Bioinformatics·Anthony M BolgerBjoern Usadel
Jun 26, 2014·Journal of Experimental Botany·Meng YangXingming Lian
Dec 17, 2014·Environmental Science & Technology·Fang-Jie ZhaoSteve P McGrath
Mar 21, 2017·Nature Plants·Dali ZengQian Qian
May 26, 2017·PloS One·Yan SongYunyun Gong
Feb 15, 2018·Nature Communications·Jin-Song LuoJi-Ming Gong
May 24, 2018·The Science of the Total Environment·Hongping ChenFang-Jie Zhao

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Citations

Aug 14, 2019·Journal of Experimental Botany·Stephan Clemens
Feb 23, 2020·Journal of Integrative Plant Biology·Xin-Yuan Huang, Fang-Jie Zhao
Jan 21, 2020·Journal of Integrative Plant Biology·Chaolei LiuZhenyu Gao
Dec 22, 2019·Scientific Reports·Alice Pita-BarbosaDavid E Salt
Apr 5, 2020·Science China. Life Sciences·Zhizhong GongJian-Kang Zhu
Aug 9, 2020·Frontiers in Plant Science·Beibei HuZhong-Hua Chen
Sep 26, 2020·Journal of Experimental Botany·Yuta Kawakami, Navreet K Bhullar
Mar 14, 2021·Ecotoxicology and Environmental Safety·Suihua HuangXiangru Tang
Oct 16, 2021·Physiologia Plantarum·Pratibha GourSaurabh Raghuvanshi
Dec 7, 2021·Frontiers in Plant Science·Jianqin XuFutong Yu

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