Natural zeolites chabazite/phillipsite/analcime increase blood levels of antioxidant enzymes.

Journal of Clinical Biochemistry and Nutrition
Giada DogliottiElena Dozio

Abstract

Imbalance between reactive oxygen species generation and antioxidant capacity induces a condition known as oxidative stress which is implicated in numerous pathological processes. In this study we evaluated whether natural zeolites chabazite/phillipsite/analcime may affect the levels of different antioxidant enzymes (gluthatione peroxidase, superoxide dismutase, gluthatione reductase), total antioxidant status and oxidative stress in 25 clinically healthy men, both non-smokers and smokers. Measurements were performed on whole blood or on plasma samples before (T0) and after 4-weeks zeolites intake (T1). At T1, gluthatione peroxidase, superoxide dismutase and gluthatione reductase increased compared to T0 levels, both considering all subjects as joint and after subdivision in non-smokers and smokers. Differently, a reduction in total antioxidant status was observed at T1. Anyway, total antioxidant status resulted higher than the reference values in both groups at each time point. A decrease in lipid peroxidation, a major indicator of oxidative stress assessed by monitoring thiobarbituric acid reactive substances, was also observed in all subjects at T1. Our results suggested that chabazite/phillipsite/analcime may help to counte...Continue Reading

References

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Citations

Aug 27, 2015·Biological Trace Element Research·Hande YapislarEmine Sonmez
Apr 10, 2018·Biomaterials Science·Lucie BacakovaIvan Jirka
Apr 20, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Andrea MastinuMaurizio Memo
Jun 11, 2020·Minerva gastroenterologica e dietologica·Marta VerneroMarco Astegiano

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