Naturally occurring furofuran lignans: structural diversity and biological activities

Natural Product Research
Wen-Hui XuQian Liang

Abstract

Furofuran lignans containing the 2,6-diaryl-3,7-dioxabicyclo[3.3.0]octane skeleton, represent one of the major subclasses of the lignan family of natural products. Furofuran lignans feature a wide variety of structures due to different substituents at aryl groups and diverse configurations at furofuran ring. Moreover, they exhibit a wide range of significant biological activities, including antioxidant, anti-inflammatory, cytotoxic, and antimicrobial activities. This review summarizes source, phytochemistry, and biological activities of 137 natural furofuran lignans isolated from 53 species in 41 genera of 27 plant families for the last 20 years, which provides a comprehensive information for further research of these furofuran lignans as potential pharmaceutical agents.

References

Dec 21, 2002·Planta medica·Elvira J De LeónM Carmen Terencio
May 24, 2003·Journal of Natural Products·Chia-Chung HouFeng-Lin Hsu
Dec 29, 2004·Journal of Natural Products·Byung-Sun MinHyeong-Kyu Lee
Apr 6, 2005·Plant Cell Reports·J MalarzW Kisiel
Jun 9, 2005·Natural Product Research·Helder L TelesDulce H S Silva
Oct 11, 2005·Archives of Pharmacal Research·Byung-Sun MinMee Ree Kim
Apr 29, 2006·Natural Product Research·Thomas J SchmidtGünter Willuhn
Jan 18, 2007·Archives of Pharmacal Research·Qing-He LiuEun-Rhan Woo
Jan 8, 2008·Chemical & Pharmaceutical Bulletin·Masanori KuroyanagiTakahisa Nakane
Mar 8, 2008·Fitoterapia·Wanda Kisiel, Klaudia Michalska
Jul 29, 2008·Journal of Agricultural and Food Chemistry·Young-Won ChinA Douglas Kinghorn
Aug 9, 2008·Journal of Agricultural and Food Chemistry·Antonio FiorentinoPietro Monaco
Dec 2, 2008·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·Rubens L Monte NetoMárcia R Oliveira
Dec 27, 2008·Bioorganic & Medicinal Chemistry Letters·Jae Yeon KimJae-Ha Ryu
Feb 26, 2009·Planta medica·Jonas da Silva MotaMaysa Furlan
May 2, 2009·Archives of Pharmacal Research·Seong Su HongBang Yeon Hwang
Mar 12, 2011·Journal of Agricultural and Food Chemistry·Ping-Chung KuoJason T C Tzen
Oct 20, 2011·Natural Product Research·Tao GuoSheng-Li Pan
Oct 26, 2011·Planta medica·Wen-Shu WangCong-Cong Shao
Dec 25, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jun LeeOk-Sun Bang
Jan 21, 2014·Chemistry & Biodiversity·Jia ZhangChangqi Zhao
Feb 19, 2014·Journal of Pharmaceutical and Biomedical Analysis·Vishal KumarNeeraj Kumar
Apr 2, 2014·Planta medica·Robert O BusseyNadja B Cech
Jul 22, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Maribel Herrera-RuizAlejandro Zamilpa
Aug 26, 2015·Journal of Natural Products·Yuanyuan LuYonghui Zhang
Feb 8, 2016·Journal of Bioscience and Bioengineering·Tomonori AsaiShin'ichiro Kajiyama
Feb 9, 2016·Journal of Natural Products·David J Newman, Gordon M Cragg
Apr 20, 2016·Journal of Natural Medicines·Huan XiongGuogang Zhang
May 10, 2016·Natural Product Reports·Rémy Bertrand TeponnoMichael Spiteller
Oct 26, 2016·Bioorganic & Medicinal Chemistry Letters·Kuo XuPei-Cheng Zhang
Nov 11, 2016·Natural Product Research·Yue-Ting LiJun Li
Jul 12, 2017·Natural Product Research·Tie LiuWen-Hui Xu
Sep 5, 2017·Chemical & Pharmaceutical Bulletin·Thi Tuyet Mai NguyenJeong Ah Kim

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Citations

Jan 9, 2019·Natural Product Research·Liping LongHuiyuan Gao
Apr 17, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ricardo López-RodríguezAlejandro Zamilpa
May 8, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Simona LucioliEmilia Caboni
May 16, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mayara Dos Santos MaiaMarcus Tullius Scotti
Jul 4, 2020·Critical Reviews in Food Science and Nutrition·Himanshu ChhillarMohd Ashraf Ashfaq
Oct 18, 2018·Frontiers in Pharmacology·Madamanchi Geethangili, Shih-Torng Ding
Mar 9, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Carmen Rodríguez-GarcíaJosé J Gaforio
Jul 7, 2020·Frontiers in Chemistry·Yang ChenShuzhong He
Feb 11, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mebeaselassie AndargiePetr Karlovsky
Jan 23, 2021·RSC Medicinal Chemistry·Godwin Akpeko DziwornuKelly Chibale
Aug 8, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Wei Li, Hye Jin Yang

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