Nature and Nurture: Effects of Affective Temperaments on Depressive Symptoms Are Markedly Modified by Stress Exposure

Frontiers in Psychiatry
Xenia GondaGyorgy Bagdy

Abstract

Lack of proper consideration of the interaction between biological and environmental factors limits our understanding of the development of depression. Our cross-sectional study investigated whether recent stress influences the effect of affective temperaments on depressive symptoms. 1015 general population participants completed the Brief Symptom Inventory to capture depressive symptoms, the List of Threatening Experiences Questionnaire to assess recent stressors, and the Temperament Evaluation of Memphis Pisa, Paris, and San Diego Autoquestionnaire to evaluate affective temperaments (TEMPS-A). Linear regression models were built to investigate the effect of temperament and stress on depression, temperament on stress, and the effect of temperament on depressive symptoms in different stress exposure groups. Recent life events and anxious, depressive, cyclothymic, and hyperthymic temperaments significantly predicted depressive symptoms, and cyclothymic, and hyperthymic temperaments significantly predicted recent life event exposure. While in case of mild stress all affective temperaments except irritable predicted depression, in case of moderate exposure only the effect of depressive, cyclothymic, and hyperthymic temperament, wh...Continue Reading

References

Apr 1, 1975·Journal of Consulting and Clinical Psychology·L R DerogatisB Wittelsberger
Jul 1, 1992·Journal of Psychiatric Research·S L BrownC R Cloninger
Jan 1, 1987·The British Journal of Psychiatry : the Journal of Mental Science·G W BrownT O Harris
Jun 17, 1994·Science·T J Bouchard
Jan 1, 1997·Annual Review of Psychology·R C Kessler
Nov 21, 1998·The Journal of Nervous and Mental Disease·K S KendlerC A Prescott
Jun 9, 1999·The American Journal of Psychiatry·K S KendlerC A Prescott
Sep 29, 2000·The American Journal of Psychiatry·P F SullivanK S Kendler
Dec 18, 2002·Journal of Neurobiology·Thomas J Bouchard, Matt McGue
Nov 24, 2004·Journal of Affective Disorders·Marko ElovainioLiisa Keltikangas-Järvinen
Mar 23, 2005·Journal of Affective Disorders·Y SakaiH Akiskal
May 15, 2007·Journal of Affective Disorders·Hagop S Akiskal, Kareen K Akiskal
Feb 27, 2009·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Gabriella JuhaszJ F William Deakin
Oct 8, 2009·Current Opinion in Psychiatry·Zoltán RihmerHagop S Akiskal
Dec 15, 2010·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·J F W DeakinI M Anderson
Jan 11, 2011·Biological Psychiatry·Gabriella JuhaszJ F William Deakin
Jan 26, 2011·Journal of Affective Disorders·Olli Kampman, Outi Poutanen
Jul 22, 2011·Journal of Affective Disorders·Gustavo H VázquezXenia Gonda
Aug 10, 2011·Molecular Psychiatry·P Sullivan, UNKNOWN 96 Psychiatric Genetics Investigators
Apr 5, 2012·Molecular Psychiatry·UNKNOWN Major Depressive Disorder Working Group of the Psychiatric GWAS ConsortiumPatrick F Sullivan
Jun 14, 2013·Journal of Affective Disorders·Tiffany A GreenwoodJohn R Kelsoe
Feb 11, 2014·Neuron·Jonathan Flint, Kenneth S Kendler
Apr 1, 2014·Journal of Affective Disorders·Janusz K RybakowskiHagop H Akiskal
Mar 3, 2018·The American Journal of Psychiatry·Roseann E PetersonKenneth S Kendler
Mar 4, 2018·Scientific Reports·Xenia GondaGyorgy Bagdy
Sep 7, 2018·Pharmacology & Therapeutics·Xenia GondaGyorgy Bagdy
Nov 7, 2018·Lancet·Gin S Malhi, J John Mann
Mar 17, 2019·Translational Psychiatry·Johan OrmelHarold Snieder

❮ Previous
Next ❯

Citations

Mar 5, 2021·The Cochrane Database of Systematic Reviews·Barbara Nussbaumer-StreitGerald Gartlehner

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.