Jul 1, 1971

Nature and self-regulated synthesis of the repressor of the hut operons in Salmonella typhimurium

Proceedings of the National Academy of Sciences of the United States of America
G R Smith, B Magasanik

Abstract

The enzymes mediating histidine utilization, coded by the hut genes, in Salmonella typhimurium are synthesized from two closely-linked operons. Results presented in this paper show that these operons are regulated by a single repressor protein. The hutC gene, coding for this repressor, is part of one of the operons. Since this same operon is sensitive to the repressor, the repressor apparently represses its own synthesis.

  • References5
  • Citations22

Mentioned in this Paper

Bacterial Proteins
Transcription Repressor/Corepressor
Alkalescens-Dispar Group
Histidine
Enzymes, antithrombotic
Science of Microbial Genetics
Aminohydrolases
Desmolases
Oxidase
Transduction, Genetic

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