Nazarov cyclization of divinyl and arylvinyl epoxides: application in the synthesis of resveratrol-based natural products

Chemistry : a European Journal
Gangarajula Sudhakar, Kovela Satish

Abstract

New variation in the Nazarov cyclization has been developed by preparing divinyl and arylvinyl epoxides as pentadienyl cation precursors for the first time. Highly substituted cyclopentadienes, hydrindienes, and indenes were synthesized to demonstrate the compatibility of this reaction with substrates bearing a variety of substitutions and having different types of epoxides. Application of this method in the synthesis of resveratrol-based natural products was also demonstrated.

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Citations

Jul 24, 2015·Organic & Biomolecular Chemistry·Gangarajula SudhakarJagadesh Babu Nanubolu
May 25, 2016·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Toshiyuki ItohMotoi Kawatsura
Sep 30, 2017·Organic & Biomolecular Chemistry·Maxim G VinogradovSergei G Zlotin
Apr 25, 2020·Organic Letters·Uttam K MishraS S V Ramasastry
Aug 19, 2017·Organic Letters·Gangarajula SudhakarJagadeesh Babu Nanubolu

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