PMID: 9176664May 1, 1997Paper

Ncx, a Hox11 related gene, is expressed in a variety of tissues derived from neural crest cells

Anatomy and Embryology
M HatanoT Tokuhisa

Abstract

We have isolated the murine homeobox gene (Ncx) that belong to a Hox11 gene family. Expression of the Ncx gene was analyzed in total RNAs from embryos by reverse transcribed polymerase chain reaction (RT-PCR). The mRNA was detected in embryos after 9.5 days of embryogenesis (E9.5) and was maximal at E12.5. The RT-PCR also detected the message in total RNAs from adrenal glands and intestine in adult mice. The expression was further examined in various tissues from embryos by in situ hybridization. It was detected in dorsal root ganglia, cranial nerve ganglia (V, IX, X), enteric nerve ganglia and adrenal glands from embryos between E9.5 and E13.5. Since its expression is restricted to tissues derived from neural crest cells, Ncx may play a role in differentiation and proliferation of neural crest lineage cells.

Citations

Jan 30, 2010·Development Genes and Evolution·Karl R WottonKatharine E Lewis
Jun 16, 2007·DNA and Cell Biology·Masayasu KitahashiMasahiko Hatano
Aug 15, 1997·The Journal of Clinical Investigation·M HatanoT Tokuhisa
May 2, 2003·Proceedings of the National Academy of Sciences of the United States of America·Kenji MizusekiYoshiki Sasai
Feb 17, 1999·Proceedings of the National Academy of Sciences of the United States of America·K KobayashiT Tokuhisa
Jul 12, 2011·Cellular and Molecular Life Sciences : CMLS·Chandrasekharan Lalitha IndulekhaJackson James
Jun 15, 2007·Journal of Pediatric Surgery·Taito AokiMasahiko Hatano
Nov 18, 2005·Journal of Pediatric Surgery·Melissa A ParisiRaj P Kapur
Jul 5, 2007·Differentiation; Research in Biological Diversity·Irina BrokhmanRonald S Goldstein
May 20, 2016·Scientific Reports·Youichi TeratakeMasahiko Hatano
Dec 19, 2001·Developmental Dynamics : an Official Publication of the American Association of Anatomists·P Andermann, E S Weinberg
Oct 31, 2002·American Journal of Medical Genetics·Ivana MateraIsabella Ceccherini
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Jan 13, 2006·The Biochemical Journal·Silvia BorghiniIsabella Ceccherini
Aug 14, 1999·The Journal of Biological Chemistry·Y IitsukaM Hatano
Jan 23, 1999·Developmental Dynamics : an Official Publication of the American Association of Anatomists·K D Patterson, P A Krieg
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