PMID: 11607554Jul 3, 1995Paper

NDR1, a locus of Arabidopsis thaliana that is required for disease resistance to both a bacterial and a fungal pathogen

Proceedings of the National Academy of Sciences of the United States of America
K S CenturyB J Staskawicz

Abstract

We have employed Arabidopsis thaliana as a model host plant to genetically dissect the molecular pathways leading to disease resistance. A. thaliana accession Col-0 is susceptible to the bacterial pathogen Pseudomonas syringae pv. tomato strain DC3000 but resistant in a race-specific manner to DC3000 carrying any one of the cloned avirulence genes avrB, avrRpm1, avrRpt2, and avrPph3. Fast-neutron-mutagenized Col-0 M2 seed was screened to identify mutants susceptible to DC3000(avrB). Disease assays and analysis of in planta bacterial growth identified one mutant, ndr1-1 (nonrace-specific disease resistance), that was susceptible to DC3000 expressing any one of the four avirulence genes tested. Interestingly, a hypersensitive-like response was still induced by several of the strains. The ndr1-1 mutation also rendered the plant susceptible to several avirulent isolates of the fungal pathogen Peronospora parasitica. Genetic analysis of ndr1-1 demonstrated that the mutation segregated as a single recessive locus, located on chromosome III. Characterization of the ndr1-1 mutation suggests that a common step exists in pathways of resistance to two unrelated pathogens.

References

Apr 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·D H Figurski, D R Helinski
Nov 1, 1991·Molecular Plant-microbe Interactions : MPMI·C JennerJ Taylor
Jan 1, 1990·Annual Review of Genetics·N T Keen
May 1, 1990·The Plant Cell·E Koch, A Slusarenko
Apr 1, 1968·Experimental Cell Research·O L GamborgK Ojima
Oct 1, 1994·Trends in Biochemical Sciences·B Kobe, J Deisenhofer
Sep 13, 1994·Proceedings of the National Academy of Sciences of the United States of America·J Glazebrook, F M Ausubel
Aug 1, 1993·The Plant Journal : for Cell and Molecular Biology·A Konieczny, F M Ausubel
May 20, 1994·Cell·R A DietrichJ L Dangl
Nov 1, 1993·The Plant Journal : for Cell and Molecular Biology·R W InnesY C Liu
Sep 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·M C WhalenB J Staskawicz
Nov 18, 1994·Science·T P DelaneyJ Ryals

❮ Previous
Next ❯

Citations

Jul 13, 2006·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·L ZhangA Kleinhofs
Oct 16, 2008·Plant Molecular Biology·Tzuu-Fen Lee, Timothy W McNellis
Jun 6, 2007·Transgenic Research·Fumiaki Katagiri, Masanao Sato
Mar 6, 1999·Current Opinion in Plant Biology·R W Innes
Mar 6, 1999·Current Opinion in Plant Biology·X Dong
Mar 6, 1999·Current Opinion in Plant Biology·J M Salmeron, B Vernooij
Nov 11, 1998·Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie·D PontierD Roby
Jul 17, 1998·Current Opinion in Biotechnology·C JiN T Keen
Jun 30, 2000·Current Opinion in Plant Biology·F F WhiteL B Johnson
Aug 25, 1999·Current Opinion in Plant Biology·P PiffanelliP Schulze-Lefert
Aug 20, 2011·Nature Immunology·Takaki MaekawaPaul Schulze-Lefert
Jan 3, 2001·The Plant Journal : for Cell and Molecular Biology·F GodardD Roby
Feb 16, 2002·The Plant Journal : for Cell and Molecular Biology·Erik A van der BiezenJonathan D G Jones
Jan 1, 2000·Molecular Plant Pathology·J E ParkerJ D Jones
Jun 17, 1998·The Plant Journal : for Cell and Molecular Biology·T W McNellisB J Staskawicz
Mar 9, 1999·The Plant Journal : for Cell and Molecular Biology·C M TobiasB J Staskawicz
Nov 26, 1999·The Plant Journal : for Cell and Molecular Biology·B S GowdaM P Timko
Nov 26, 1999·The Plant Journal : for Cell and Molecular Biology·W GassmannB J Staskawicz
Nov 9, 2000·The Plant Journal : for Cell and Molecular Biology·J DewdneyF M Ausubel
Aug 8, 2001·The Plant Journal : for Cell and Molecular Biology·M TronchetD Roby
Mar 5, 2002·The Plant Journal : for Cell and Molecular Biology·Jack R PeartDavid C Baulcombe
Jul 22, 2010·Proceedings of the National Academy of Sciences of the United States of America·Zhaohai ZhuYuelin Zhang
Jul 21, 2012·Plant & Cell Physiology·Tabea WeihmannXin Li
Mar 15, 2012·Molecular Plant-microbe Interactions : MPMI·Walter Gassmann, Saikat Bhattacharjee
Feb 10, 2012·Molecular Plant-microbe Interactions : MPMI·Manon MoreauMathilde Fagard
Feb 22, 2005·Molecular Plant-microbe Interactions : MPMI·Mark BennettMurray Grant
Nov 1, 2005·Molecular Plant-microbe Interactions : MPMI·Karolina M PajerowskaChristiane Gebhardt
Oct 9, 2007·Molecular Plant-microbe Interactions : MPMI·Min Woo LeeJean T Greenberg
Sep 13, 2008·Molecular Plant-microbe Interactions : MPMI·Ruth K GengerAndrew F Bent
Oct 10, 2008·Molecular Plant-microbe Interactions : MPMI·Marco LoehrerUlrich Schaffrath
Dec 9, 2008·Molecular Plant-microbe Interactions : MPMI·Da-Qi FuAardra Kachroo
Apr 16, 2002·Molecular Plant-microbe Interactions : MPMI·Katherine A ShenRichard W Michelmore

❮ Previous
Next ❯

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.