PMID: 11341244May 9, 2001Paper

Near 10-year and longer periods modulate circadians: intersecting anti-aging and chronoastrobiological research

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
F HalgbergO Schwrtzkopff

Abstract

Biological cycles with relatively long and some unusual periods in the range of the half-week, the half-year, years, or decades are being discovered. Their prior neglect constituted a confounder in aging and much other research, which then"flew blind" concerning the uncertainties associated with these cycles when they are not assessed. The resolution of more about 10-year and other cycles, some reported herein, replaces the admission of complete unpredictability, implied by using the label "secularity." Heretofore unaccounted-for variability becomes predictable insofar as it proves to be rhythmic and is mapped systematically to serve as a battery of useful reference values. About 10-year cycles in urinary 17-ketosteroid excretion and in heart rate and its variability, among others, are aligned with cycles of similar length in mortality from myocardial infarction. Associations accumulate between cycles of natural physical time structures, chronomes such as the 10.5-year (circadecennian) Schwabe and the 21-year (circavigintunennian) Hale cycles of solar activity, and chronomes in biota. There are about 50-year (circasemicentennian) cycles in mortality from stroke in Minnesota and in the Czech Republic and also in human morphology...Continue Reading

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Citations

Oct 24, 2003·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Sylvain Nintcheu-FataEarl Bakken
Oct 24, 2003·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Germaine CornélissenEarl E Bakken
Oct 24, 2003·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Yoshihiko WatanabeKuniaki Otsuka
Oct 24, 2003·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Christian MaschkeFranz Halberg
Oct 24, 2003·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Franz HalbergEarl E Bakken
Jun 13, 2002·Clinical and Experimental Pharmacology & Physiology·Keiko UezonoPietro Cugini
Feb 9, 2005·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Franz HalbergChristian Hamburger
Jan 20, 2004·Journal of Circadian Rhythms·Franz HalbergJarmila Siggelova
Dec 3, 2003·Journal of Experimental Therapeutics & Oncology·Franz Halberg Governor Shri Vishnu Kant Shastri
Nov 14, 2013·History of Geo- and Space Sciences·F HalbergG Cornelissen
Jan 15, 2021·F1000Research·Stella GeronikolouGeorge Chrousos

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