Near, far, wherever you are: simulations on the dose efficiency of holographic and ptychographic coherent imaging

Journal of Applied Crystallography
Ming DuChris Jacobsen

Abstract

Different studies in X-ray microscopy have arrived at conflicting conclusions about the dose efficiency of imaging modes involving the recording of intensity distributions in the near (Fresnel regime) or far (Fraunhofer regime) field downstream of a specimen. A numerical study is presented on the dose efficiency of near-field holography, near-field ptychography and far-field ptychography, where ptychography involves multiple overlapping finite-sized illumination positions. Unlike what has been reported for coherent diffraction imaging, which involves recording a single far-field diffraction pattern, it is found that all three methods offer similar image quality when using the same fluence on the specimen, with far-field ptychography offering slightly better spatial resolution and a lower mean error. These results support the concept that (if the experiment and image reconstruction are done properly) the sample can be near or far; wherever you are, photon fluence on the specimen sets one limit to spatial resolution.

References

Aug 1, 1982·Journal of Microscopy·W O Saxton, W Baumeister
Feb 1, 1995·Quarterly Reviews of Biophysics·J KirzM Howells
Aug 18, 2004·Journal of Synchrotron Radiation·Qun ShenPierre Thibault
Aug 25, 2004·Physical Review Letters·H M L Faulkner, J M Rodenburg
Aug 30, 2005·Journal of Structural Biology·Marin van Heel, Michael Schatz
Jun 22, 2006·Acta Crystallographica. Section A, Foundations of Crystallography·Pierre ThibaultDavid Sayre
Dec 21, 2006·Acta Crystallographica. Section A, Foundations of Crystallography·Garth WilliamsIan Robinson
Mar 16, 2007·Physical Review Letters·J M RodenburgI Johnson
Jun 12, 2008·Optics Express·Manuel Guizar-Sicairos, James R Fienup
Jul 19, 2008·Science·Pierre ThibaultFranz Pfeiffer
Feb 10, 2009·Ultramicroscopy·Pierre ThibaultFranz Pfeiffer
Jun 23, 2009·Ultramicroscopy·Andrew M Maiden, John M Rodenburg
Mar 1, 2009·Journal of Electron Spectroscopy and Related Phenomena·M R HowellsD Starodub
Dec 18, 2010·Optics Express·Xiaojing HuangChris Jacobsen
Nov 29, 2012·Optics Express·Pierre GodardJohn Rodenburg
Jun 6, 2013·Optics Express·Fucai ZhangJohn M Rodenburg
Jun 13, 2014·Optics Express·Xiaojing HuangYong S Chu
Aug 15, 2014·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Alden S Jurling, James R Fienup
Sep 2, 2014·Journal of Synchrotron Radiation·Mikael ErikssonChristoph Quitmann
Feb 14, 2015·Physical Review Letters·M BartelsT Salditt
Jan 4, 2017·Acta Crystallographica. Section A, Foundations and Advances·T JahnT Salditt
Apr 7, 2017·Journal of Applied Crystallography·Johannes Hagemann, Tim Salditt
Jul 29, 2017·Physical Review. B·Junjing DengChris Jacobsen
Jun 30, 2019·Optics Express·Saugat KandelYoussef S G Nashed

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Citations

Jan 6, 2021·Journal of Synchrotron Radiation·Panpan HuangChris Jacobsen
May 7, 2021·Journal of Applied Crystallography·Ming DuChris Jacobsen

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Methods Mentioned

BETA
X-ray

Software Mentioned

TensorFlow

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