Near-infrared fluorescence with indocyanine green for diagnostics in urology: initial experience

Urologia
Andrey O MorozovEugene S Sirota

Abstract

Fluorescence imaging with indocyanine green is used in urology for the detection of sentinel lymph nodes and identification of prostate margins in radical prostatectomy for delineation of resection zone and selective clamping of vessels in partial nephrectomy; for identification and evaluation of length of ureteral strictures; for assessment of perfusion and viability of anastomoses during reconstructive stage of cystectomy. Safety of this technique is proven, while its diagnostic value and usefulness is still controversial. This pilot study of using the SPY Elite Fluorescence Imaging System for diagnostics was performed in the I.M. Sechenov First Moscow State Medical University. Ten patients were enrolled: four patients underwent retropubic RP and lymph node dissection, five patients underwent partial nephrectomy, and one patient underwent ureteroplasty. Fluorophore was injected transrectally with TRUS guidance during RP in order to assess the lymph nodes. During partial nephrectomy, the compound was injected intravenously to differentiate the tumor from parenchyma by its blood supply. During ureteroplasty, the indocyanine green solution was injected into the renal pelvis to dye the ureter and locate the stricture. Sensitivity...Continue Reading

References

Jan 19, 2012·Journal of Endourology·Scott TobisDragan Golijanin
Sep 16, 2014·European Urology·Ziho LeeDaniel D Eun
Dec 3, 2014·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·T AboT Nagayasu
Jan 20, 2015·Annals of Surgery·Eben L RosenthalKurt R Zinn

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Citations

Jun 26, 2018·Journal of Surgical Oncology·Labrinus van ManenJan Sven David Mieog
Jan 16, 2019·Nature Reviews. Urology·Fijs W B van LeeuwenTobias Maurer
Dec 31, 2019·Case Reports in Urology·Ali HajiranAdam Luchey

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Methods Mentioned

BETA
fluorescence imaging
surgical resection
dissection

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