Near-Infrared Light Excited and Localized Surface Plasmon Resonance-Enhanced Photoelectrochemical Biosensing Platform for Cell Analysis

Analytical Chemistry
Ruyan LiZhihui Dai

Abstract

Under near-infrared (NIR) light of 810 nm wavelength for irradiation, a very simple and highly sensitive photoelectrochemical (PEC) biosensing platform has been established using the localized surface plasmon resonance effect of Au nanoparticles (NPs) as signal amplification for the nondestructive analysis of living cells. The water-dispersible Ag2S quantum dots (QDs) synthesized by a one pot method were employed as photoelectrochemically active species, and they exhibited excellent PEC properties irradiated with NIR light which was chosen due to the obvious absorption and fluorescent emission in the NIR light region. After the incorporation of Au NPs on the Ag2S QDs modified ITO electrode, the photoelectric conversion efficiency was greatly increased, at ∼2.5 times that of the pure Ag2S QDs modified electrode. Additionally, 4-mercaptophenylboronic acid (MPBA) molecules, as recognition elements, self-assembled on the electrode surface through Au-S bonds. On the basis of the chemical reaction between sialic acid on the cytomembranes and boric acid of MPBA, the very simple PEC biosensing platform was used for the quantitative determination of MCF-7 cells and dynamic evaluation of cell surface glycan expression under the external ...Continue Reading

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Citations

Oct 1, 2019·Chemistry : a European Journal·Lufang ZhaoYuanjian Zhang
Feb 20, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Linzheng MaJun-Jie Zhu
Mar 13, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Zhenli Qiu, Dianping Tang
Jul 14, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Wen-Chao GengYong-Jun Li
Apr 5, 2020·Mikrochimica Acta·Junjun LuoMinghui Yang
May 7, 2020·Frontiers in Chemistry·Zhengdi WangMin Wei

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