Near-infrared spectroscopy for the detection of vulnerable coronary artery plaques

Journal of the American College of Cardiology
Jay D CaplanJames E Muller

Abstract

This review describes efforts to use near-infrared (NIR) spectroscopy to identify chemical components of coronary artery plaques as a means to assess vulnerability. Near-infrared spectroscopy has been well-validated by the physical sciences as a method to characterize chemical composition of various bio-materials and could be ideal to detect vulnerable coronary plaques in patients. Recent studies in aortic and coronary artery autopsy specimens have confirmed the ability of the technique to identify lipid-rich thin-cap fibroatheromas through blood. A catheter-based system has been developed to address the challenges-of access to the coronary artery, blood, motion, and the need to scan-that must be overcome for use in patients. Initial clinical experience in six patients with stable angina demonstrates that high-quality NIR spectra can be safely obtained. Additional studies are planned to validate the ability of the technique to identify lipid-rich coronary artery plaques and ultimately link chemical characterization with subsequent occurrence of an acute coronary syndrome.

Citations

Nov 6, 2008·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Kamran AkramSzilard Voros
Aug 7, 2013·Journal of Cardiovascular Translational Research·Vivian G NgAlexandra J Lansky
May 30, 2009·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Joseph W VillardMarc D Feldman
Aug 14, 2010·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Somjot S BrarGregg W Stone
Sep 11, 2007·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Sergio WaxmanJay D Caplan
Dec 1, 2008·Biomarkers in Medicine·Stéphane NobleJean-Claude Tardif
Sep 17, 2013·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Debdoot SheetAmin Katouzian
Oct 11, 2014·Photoacoustics·Krista JansenGijs van Soest
Feb 18, 2016·Current Cardiology Reports·Jonathan A BattyVijay Kunadian
Jan 23, 2010·Current Medical Research and Opinion·Ozgur BayturanStephen J Nicholls
Jul 15, 2015·The International Journal of Cardiovascular Imaging·Charis CostopoulosMartin R Bennett
Feb 22, 2012·Translational Research : the Journal of Laboratory and Clinical Medicine·Chris T Longenecker, Brian D Hoit
May 6, 2010·Analytica Chimica Acta·Zou XiaoboMao Hanpin
Dec 8, 2009·Cardiology Clinics·Pedro R Moreno
Jan 22, 2008·International Journal of Cardiology·Kiat Tsong Tan, Gregory Y H Lip
Jul 21, 2007·The Medical Clinics of North America·Mario GösslAmir Lerman
Nov 1, 2008·Journal of Interventional Cardiology·Sergio Waxman
Feb 22, 2008·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·John J YoungGregg W Stone
Aug 13, 2011·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Shann S YuTodd D Giorgio
Apr 16, 2016·Trends in Cardiovascular Medicine·Csilla CelengPál Maurovich-Horvat
Sep 4, 2010·Journal of Magnetic Resonance Imaging : JMRI·Jinnan WangChun Yuan
Aug 13, 2008·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Amin KatouzianStéphane G Carlier
Mar 6, 2012·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Amin KatouzianAndrew F Laine
Apr 8, 2016·JACC. Cardiovascular Imaging·Aditya S BharadwajAnnapoorna S Kini
Sep 1, 2015·Pharmacological Reports : PR·Katarzyna M MarzecMalgorzata Baranska
Apr 9, 2016·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Matthew D SayboltRobert L Wilensky
Jun 6, 2009·Journal of the American College of Cardiology·Susan S KimBradley P Knight
May 14, 2011·Journal of the American College of Cardiology·David VancraeynestJean-Louis J Vanoverschelde
Sep 23, 2008·Journal of Vascular Surgery·Bas M Wallis de VriesClark J Zeebregts
Sep 17, 2011·JACC. Cardiovascular Imaging·Melissa J SuterGuillermo J Tearney
May 18, 2016·Ultrasound in Medicine & Biology·Verya DaeichinGijs van Soest
May 27, 2016·Nature Reviews. Cardiology·Marc R DweckDaniel Berman

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.