Near-term forecasts of influenza-like illness: An evaluation of autoregressive time series approaches.

Epidemics
Sasikiran Kandula, Jeffrey Shaman

Abstract

Seasonal influenza in the United States is estimated to cause 9-35 million illnesses annually, with resultant economic burden amounting to $47-$150 billion. Reliable real-time forecasts of influenza can help public health agencies better manage these outbreaks. Here, we investigate the feasibility of three autoregressive methods for near-term forecasts: an Autoregressive Integrated Moving Average (ARIMA) model with time-varying order; an ARIMA model fit to seasonally adjusted incidence rates (ARIMA-STL); and a feed-forward autoregressive artificial neural network with a single hidden layer (AR-NN). We generated retrospective forecasts for influenza incidence one to four weeks in the future at US National and 10 regions in the US during 5 influenza seasons. We compared the relative accuracy of the point and probabilistic forecasts of the three models with respect to each other and in relation to two large external validation sets that each comprise at least 20 other models. Both the probabilistic and point forecasts of AR-NN were found to be more accurate than those of the other two models overall. An additional sub-analysis found that the three models benefitted considerably from the use of search trends based 'nowcast' as a pr...Continue Reading

Citations

Sep 29, 2019·Proceedings of the National Academy of Sciences of the United States of America·Johannes Bracher
Nov 5, 2020·Journal of the Indian Institute of Science·Aniruddha AdigaAnil Vullikanti
Mar 8, 2021·The Science of the Total Environment·Feihu YangJan Sundell
Dec 14, 2021·Frontiers in Immunology·Rama K MallampalliJames D Londino
Feb 1, 2022·PLoS Computational Biology·Dave Osthus

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