Necessity of meningococcal gamma-glutamyl aminopeptidase for Neisseria meningitidis growth in rat cerebrospinal fluid (CSF) and CSF-like medium

Journal of Bacteriology
Hideyuki TakahashiHaruo Watanabe


The growth of a gamma-glutamyl aminopeptidase (GGT)-deficient Neisseria meningitidis strain was much slower than that of the parent strain in rat cerebrospinal fluid (CSF) and in a synthetic CSF-mimicking medium, and the growth failure was suppressed by the addition of cysteine. These results suggested that, in the environment of cysteine shortage, meningococcal GGT provided an advantage for meningococcal multiplication by supplying cysteine from environmental gamma-glutamyl-cysteinyl peptides.


Mar 1, 1975·Journal of Neurochemistry·T L PerryJ Kennedy
Apr 1, 1989·Clinical Microbiology Reviews·R J Arko
May 1, 1985·Journal of Clinical Microbiology·J D Brown, K R Thomas
Jan 1, 1983·Annual Review of Microbiology·W Harder, L Dijkhuizen
Oct 1, 1984·Journal of Clinical Microbiology·P P WelbornN Ellison-Birang
Feb 1, 1995·Microbiology·F SchutR A Prins
Jun 26, 1999·Molecular Microbiology·A B Schryvers, I Stojiljkovic
Jan 11, 2000·Clinical Microbiology Reviews·M van DeurenJ W van der Meer
Oct 10, 2001·The Journal of Immunology : Official Journal of the American Association of Immunologists·M M PolflietT K van den Berg
May 23, 2002·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Gordana ZunićSlavica Spasić
Mar 1, 1962·Journal of Bacteriology·B W CATLIN, G M SCHLOER
Jun 1, 1942·Journal of Bacteriology·I D Frantz


Jul 25, 2009·Nihon saikingaku zasshi. Japanese journal of bacteriology·Hideyuki Takahashi
Oct 6, 2005·Journal of Biochemistry and Molecular Biology·Hyun-Jung KangChang-Jin Lim
Apr 11, 2014·TheScientificWorldJournal·Sharath Balakrishna, Asmita Prabhune
Nov 11, 2008·Cell Host & Microbe·Dirk HofreuterJorge E Galán
Jul 16, 2014·Expert Review of Proteomics·Myron Christodoulides

Related Concepts

Cerebrospinal Fluid
Cysteine Hydrochloride
Gamma-glutamyl transferase
Neisseria meningitidis
Rats, Laboratory

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