PMID: 3754374Jan 1, 1986Paper

Necrosis of the fetal brain stem with cerebellar hypoplasia

Acta Neuropathologica
E C GessagaH Urich

Abstract

Two neonates are presented with intrauterine necrosis of the brain stem. In one of the necrosis and calcification were multifocal and extended from the thalamus to the medulla oblongata. In the other the process was limited to the medulla, but was associated with severe hypoplasia of the nuclei pontis. In both cases the cerebellum was hypoplastic and immature for the gestational age. The connection between the two lesions remains obscure, and two hypotheses are discussed. One hypothesis ascribes the delay in cerebellar development to subliminal damage caused by the same insult that produced the brain-stem lesions, the other considers the possible effects of partial deafferentation on the maturation of the cerebellum.

References

Feb 1, 1977·Archives of Neurology·R E Myers, S Yamaguchi
Oct 1, 1979·Acta Neuropathologica·J TowfighiR Vannucci
Feb 1, 1977·Archives of Neurology·N ThakkarM Ambler
Sep 26, 1977·Acta Neuropathologica·R D AdamsT Rabinowicz
Aug 1, 1970·The Journal of Comparative Neurology·P Rakic, R L Sidman
Jan 1, 1982·Acta Neuropathologica·E R WilsonJ F Schwartz
Jan 1, 1980·Acta Neuropathologica·R C Janzer, R L Friede
Jan 1, 1963·Archiv für Psychiatrie und Nervenkrankheiten, vereinigt mit Zeitschrift für die gesamte Neurologie und Psychiatrie·H J COLMANT, H WEVER

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Citations

Jan 1, 1992·Acta Neuropathologica·J PindurN E Rance
Jan 1, 1994·Neuroradiology·N deSouzaT Cox
Jan 1, 1986·Acta Neuropathologica·A M Strefling, H Urich
May 1, 1991·American Journal of Obstetrics and Gynecology·L M HillJ Hixson
Jul 1, 1989·Journal of Child Neurology·K D MathewsJ W Hanson
Mar 27, 1998·Prenatal Diagnosis·J B RobinsD Martinez
May 8, 2000·Stroke; a Journal of Cerebral Circulation·R De CaroV Macchi

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