Necrotizing enterocolitis in full-term infants: case-control study and review of the literature

Journal of Perinatology : Official Journal of the California Perinatal Association
Ayala Maayan-MetzgerJacob Kuint

Abstract

To examine the increasing number of full-term infants at our hospital exhibiting necrotizing enterocolitis (NEC) in order to characterize these cases and to discover common risk factors. Medical charts were reviewed for all full-term infants (gestational age > 36 weeks) that were born in our institution during a 5-year period (from January 1, 1998 to December 31, 2002) and that developed definite NEC. Data regarding the rate of Cesarean section (CS) in our institution over the study period and five years prior to the study was also recorded. During the 5 years of the study, 14 full-term infants were found to have NEC. The incidence of NEC in full-term infants increased from 0.16 to 0.71 per 1000 live births in the 5-year period. Mean birth weight was 2829 g. All the NEC infants except one were delivered by CS, and all of them were fed either with a mixture of breast milk and formula or entirely by formula. Seven of the infants (50%) had no major known risk factors predisposing them for NEC. Mean age of disease onset was very early (4.1 days) in most of the infants (12 infants), and the colon was the main NEC site. The short-term outcome was favorable in all but one case, which required explorative laparotomy for intestinal perf...Continue Reading

References

Sep 1, 1976·The Journal of Pediatrics·R A PolinW C Heird
Apr 1, 1992·Archives of Disease in Childhood·P J Beeby, H Jeffery
May 1, 1990·American Journal of Surgery·D A AndrewsE I Hatch
May 1, 1988·American Journal of Diseases of Children·T E WiswellD J Tuttle
Aug 1, 1995·Diseases of the Colon and Rectum·A KabeerC Coren
Jan 1, 1997·Biology of the Neonate·E Martinez-TalloE Bancalari
Oct 17, 1998·Journal of Perinatal Medicine·D G SweetC Mulholland
Feb 13, 2001·Journal of Paediatrics and Child Health·S Ng
Apr 24, 2001·Current Opinion in Pediatrics·M S Caplan, T Jilling
Mar 7, 2003·The New England Journal of Medicine·Howard Minkoff, Frank A Chervenak

❮ Previous
Next ❯

Citations

Aug 25, 2010·Pediatric Radiology·Hwa-Young KimGyeong Hoon Kang
Apr 28, 2009·Pediatric Surgery International·Yigit S GunerLisa K Kelly
Oct 10, 2006·Lancet·Patricia W Lin, Barbara J Stoll
Apr 4, 2012·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Sheila M GephartMelissa D Halpern
Jul 21, 2011·Journal of Paediatrics and Child Health·Ayelet Ben-Sasson
May 6, 2008·BMJ : British Medical Journal·M Stephen Murphy
Mar 5, 2011·Pediatric Research·Patrycja J PuimanIngrid B Renes
Mar 30, 2007·Journal of Perinatology : Official Journal of the California Perinatal Association·D K LambertJ Burnett
Jun 18, 2008·Journal of Perinatology : Official Journal of the California Perinatal Association·C J HunterV Camerini
Jun 18, 2008·Journal of Perinatology : Official Journal of the California Perinatal Association·C J HunterH R Ford
May 3, 2013·Journal of Perinatology : Official Journal of the California Perinatal Association·C CozziC Cua
Jan 19, 2011·Indian Journal of Pediatrics·Lalitha Krishnan, Anil Pathare
Nov 8, 2013·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Salih KalayNihal Oygur
Jan 11, 2014·Pathophysiology : the Official Journal of the International Society for Pathophysiology·David A Clark, Upender K Munshi
Nov 27, 2015·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Emmanouela SdonaA Malamitsi-Puchner
Feb 19, 2013·Clinics in Perinatology·Robert D ChristensenPhillip V Gordon
Jul 24, 2010·The Journal of Pediatrics·Cassandra D JosephsonAkhil Maheshwari
Jan 12, 2008·Life Sciences·Peter J GiannoneLoren E Wold
Oct 24, 2007·Emergency Medicine Clinics of North America·Jeffrey P Louie
Oct 16, 2007·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·N Montjaux-RégisC Casper
Apr 15, 2015·Journal of the American College of Surgeons·Jeremy G FisherTom Jaksic
Feb 27, 2008·Acta Paediatrica·Jacob KuintAyala Maayan-Metzger
Aug 10, 2011·Emergency Medicine Australasia : EMA·Davinder Gill
Dec 13, 2005·Journal of Pediatric Surgery·Hiroaki KomuroMichio Kaneko
Feb 19, 2008·Clinics in Perinatology·Pinchi S SrinivasanAntoni D'Souza
Dec 3, 2016·Pharmacoepidemiology and Drug Safety·Ann W McMahonDiva D De Leon
Mar 13, 2018·AJR. American Journal of Roentgenology·Anh-Vu NgoGrace S Phillips
Feb 25, 2010·Journal of Pediatric Gastroenterology and Nutrition·C DupontPh Benhamou
May 27, 2014·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Sheila M GephartBrittany Krisman
Oct 3, 2019·Pediatrics in Review·Fiona WertheimerVictoria Niklas
Mar 8, 2020·JPEN. Journal of Parenteral and Enteral Nutrition·Lyvonne N TumeUNKNOWN Paediatric Intensive Care Society Study Group (PICS-SG)
Aug 29, 2020·Pediatric Research·Jae H KimJennifer Canvasser
Aug 3, 2020·Acta Paediatrica·William CalvertPaul D Losty
Jan 27, 2021·Seminars in Perinatology·Katherine E ChettaCarol L Wagner
Feb 3, 2021·Journal of Pediatric Surgery·Noah KinstlingerSteven H Borenstein
Mar 16, 2021·Frontiers in Pediatrics·Julia M PantaloneLiza Konnikova
Jun 1, 2016·Pediatrics·Nansi S BoghossianUNKNOWN Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network

❮ Previous
Next ❯

Methods Mentioned

BETA
X-ray

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Perinatology : Official Journal of the California Perinatal Association
D K LambertJ Burnett
Journal of Pediatric Surgery
Daniel J OstlieCharles L Snyder
American Journal of Surgery
D A AndrewsE I Hatch
© 2022 Meta ULC. All rights reserved