Necrotizing granulomata in the lung preceding colonic involvement in 2 patients with Crohn's disease

Respiration; International Review of Thoracic Diseases
Tiberiu ShulimzonIssahar Ben-Dov

Abstract

Extraintestinal involvement, including the chest, is common in the late course of Crohn's disease. We describe 2 female patients in whom the course of the disease was unique in two aspects: (1) each had a pulmonary mass with granulomatous inflammation and necrosis, and (2) these findings had preceded the colonic involvement by 5 years. This sequence supports some of the theories on the pathogenesis of Crohn's disease and on its possible relation with sarcoidosis, another idiopathic granulomatous disease.

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Citations

Nov 1, 2012·World Journal of Gastroenterology : WJG·De-Gan LuZhen-Fang Li
Jan 15, 2014·World Journal of Gastroenterology : WJG·De-Gan LuCai-Qing Zhang
Oct 12, 2019·Journal of Crohn's & Colitis·Elena EliadouUNKNOWN ECCO CONFER COMMITTEE
Jul 27, 2021·Frontiers in Medicine·Marc A Judson

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