Necrotizing Pancreatitis: Current Management and Therapies

Clinical Endoscopy
Christine BoumitriMichel Kahaleh

Abstract

Acute necrotizing pancreatitis accounts for 10% of acute pancreatitis (AP) cases and is associated with a higher mortality and morbidity. Necrosis within the first 4 weeks of disease onset is defined as an acute necrotic collection (ANC), while walled off pancreatic necrosis (WOPN) develops after 4 weeks of disease onset. An infected or symptomatic WOPN requires drainage. The management of pancreatic necrosis has shifted away from open necrosectomy, as it is associated with a high morbidity, to less invasive techniques. In this review, we summarize the current management and therapies for acute necrotizing pancreatitis.

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Citations

Aug 26, 2018·Journal of Gastroenterology and Hepatology·Li TaoBin Wu
Jun 4, 2019·Journal of Gastroenterology and Hepatology·Silvia WürstleJochen Schneider
Jun 18, 2019·The American Journal of Gastroenterology·Elaina VivianPaul Tarnasky
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Mar 26, 2021·World Journal of Emergency Surgery : WJES·Massimo SartelliPierluigi Viale
Sep 4, 2020·American Journal of Surgery·Shravan Leonard-MuraliArielle H Gupta
Nov 26, 2020·Journal of Clinical Gastroenterology·Mihajlo GjeorgjievskiMichel Kahaleh

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