PMID: 9548101Apr 21, 1998Paper

Necrotizing perineal infections (Fournier's disease): old remedies for an old disease

International Journal of Colorectal Disease
I N Nomikos

Abstract

Perineoscrotal gangrene (Fournier's disease, a specific type of necrotizing fasciitis) is a rare and potentially fatal clinical entity characterized by progressive spread of necrosis in the skin and subcutaneous tissues combined with severe systemic sepsis. We analyzed retrospectively seven patients with perineoscrotal gangrene, illustrating the various clinical presentations, problems in management, and specific approaches to therapy. On admission all patients were evaluated as being in critical condition, having severe systemic disease and rapidly advancing gangrene. After hemodynamic stability was achieved broad spectrum antibiotics were started, and aggressive surgical treatment initiated. In all the patients the infection originated from the anorectal area and proved to be polymicrobial in nature. Six patients survived and were able to be discharged from hospital there was one death on the fifth postoperative day due to pulmonary embolism. The crucial points in the management of this infection remains early diagnosis, wide and repeated surgical débridements, and appropriate antibiotic therapy.

Citations

Jul 20, 2000·Primary Care Update for Ob/Gyns·D L Ripley
Dec 21, 2002·International Journal of Dermatology·Hugo CabreraCristina Echeverría
Feb 27, 2013·International Surgery·Cyrus C Chan, Mallory Williams
Jan 27, 2007·Plastic and Reconstructive Surgery·Pedro Costa FerreiraPedro Natividade da Silva
Jun 27, 2007·Surgery Today·Mahmut BasogluDurkaya Oren
Oct 8, 2004·Journal of Wound Care·I Poromanski, A Andriessen
Sep 27, 2000·Diseases of the Colon and Rectum·R J YaghanI Bani-Hani

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