Necrotizing soft tissue infection caused by Serratia marcescens: A case report and literature review

Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
Hideharu HagiyaKazunori Tomono

Abstract

A 64-year-old man with advanced liver cirrhosis was transferred to an emergency center due to septic shock and markedly inflamed left leg. Under a clinical diagnosis of necrotizing soft tissue infection (NSTI), the patient undertook intensive therapy but died 25 h after arrival. The pathogenic organism, Serratia marcescens, was later isolated from blood and soft tissue cultures. NSTI is very rarely associated with S. marcescens. A literature review showed that only 16 such cases, including our case, have been reported to date. Our case is the first evidence of an S. marcescens NSTI in a patient with liver cirrhosis. S. marcescens NSTI has an extremely high mortality rate; total mortality and mortality in cases involving the extremities were 75% (12 of 16 cases) and 83.3% (10 of 12 cases), respectively. Physicians need to be aware that S. marcescens can induce fatal infections in community patients.

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Citations

Apr 2, 2019·Journal of Investigative Medicine High Impact Case Reports·Deeti J PithadiaStephanie L Baer
May 1, 2020·The Journal of Investigative Dermatology·Alexander SalavaAntti Lauerma

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