Necrotizing soft tissue infections developing from pressure ulcers

Journal of Tissue Viability
Fumihiro MizokamiZenzo Isogai

Abstract

Necrotizing soft tissue infections (STIs) are serious complications that may arise from pressure ulcers. However, there are few studies on this important issue. In addition, diagnostic criteria for necrotizing STIs developing from pressure ulcers and infected pressure ulcers are not well established. We defined necrotizing STIs developing from pressure ulcers based on clinical findings. Based on the definition, we retrospectively analyzed the medical records of 24 elderly patients with this condition to determine patient age, gender, comorbid disease, laboratory findings, wound location, bacteriology, and treatment outcomes. In the examined population, necrotizing STIs developed primarily from pressure ulcers over the sacrum. Dementia and diabetes mellitus were also frequently observed in patients with necrotizing STIs. The average Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score was relatively low. Bacterial cultures from the debrided deep tissues exhibited mixed infections of gram-positive cocci and gram-negative bacilli, except 1 case. Anaerobic pathogens were isolated from 18 patients (72%), and 7 patients (29%) developed bacteremia. None of the cases were preceded by wounds dominated by granulation tissue...Continue Reading

References

May 1, 1995·Annals of Surgery·C R McHenryM A Malangoni
Jun 1, 1999·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·P W SmithS B Black
Nov 20, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Nigel J Livesley, Anthony W Chow
Dec 17, 2002·Journal of the American Pharmaceutical Association : APhA·Gordon G Liu, Dale B Christensen
May 31, 2011·Journal of the American Medical Directors Association·Paul DrinkaChristopher J Crnich
May 24, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Benjamin A Lipsky Infectious Diseases Society of America
May 24, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Benjamin A Lipsky Infectious Diseases Society of America

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Citations

Jan 17, 2015·Frontiers in Surgery·Evangelos P MisiakosAnastasios Machairas
Nov 26, 2015·The International Journal of Lower Extremity Wounds·Xiaofang Sun, Ting Xie
Sep 2, 2021·Revista brasileira de enfermagem·Tatiana Neves FigueiraMaria Lígia Dos Reis Bellaguarda

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