Negative affect is associated with development and persistence of chemical intolerance: a prospective population-based study

Journal of Psychosomatic Research
Sine SkovbjergJesper Elberling

Abstract

Chemical intolerance (CI) is characterised by negative health effects attributed to a heightened responsiveness to common airborne chemicals. This longitudinal study explored the hypothesised role of negative affect in the development and persistence of CI in a general population. A general population sample aged 19 to 72 years was examined in 2006-2008 and again in 2011-2012. Longitudinal data on CI were analysed with the purpose of examining baseline negative affect as a risk factor for having developed CI at 5-year follow-up and for reporting persistent CI. Participants were classified as reporting no signs of CI, having symptoms of CI and as being a likely CI case based on self-reported reactions to 11 common chemical exposures, symptoms related to chemical exposures and daily life adjustments attributed to reactions when exposed to chemicals. A total of 69.4% of the participants who had reported CI at baseline also reported CI at follow-up. In participants with no baseline CI, 15.5% reported CI at follow-up and 18.1% reported symptoms related to chemicals but no daily life adjustments. Baseline negative affect was positively and statistically significantly associated with both development and persistence of CI. Initial rep...Continue Reading

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Citations

Nov 26, 2015·The Science of the Total Environment·Jarry T PorsiusDanielle R M Timmermans
Apr 30, 2016·International Archives of Occupational and Environmental Health·Marlene PacharraChristoph van Thriel
Dec 8, 2016·Journal of Toxicology and Environmental Health. Part a·Marlene PacharraChristoph van Thriel
Nov 8, 2017·Journal of Occupational and Environmental Medicine·Sabrina Rossi, Alessio Pitidis
Feb 7, 2020·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Katharina HarterClaudia Traidl-Hoffmann
Feb 7, 2020·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Katharina HarterClaudia Traidl-Hoffmann
Mar 18, 2017·Risk Analysis : an Official Publication of the Society for Risk Analysis·Jarry T PorsiusDanielle R M Timmermans
Oct 24, 2019·Environmental Health and Preventive Medicine·Kenichi AzumaKou Sakabe

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