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Negative feedback regulation of Dicer-Like1 in Arabidopsis by microRNA-guided mRNA degradation

Current Biology : CB

Apr 29, 2003

Zhixin XieJames C. Carrington

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Abstract

Formation of microRNA (miRNA) requires an RNaseIII domain-containing protein, termed DICER-1 in animals and DICER-LIKE1 (DCL1) in plants, to catalyze processing of an RNA precursor with a fold-back structure. Loss-of-function dcl1 mutants of Arabidopsis have low levels of miRNA and exhi...read more

Mentioned in this Paper

Mutant
Oligonucleotide Primers
Arabidopsis
HC-Pro
Feedback, Biochemical
RNA, Small Temporal
RNA Instability
Back Structure, Including Back of Neck
RNA
Suppressor
260
Paper Details
References
  • References19
  • Citations252
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Negative feedback regulation of Dicer-Like1 in Arabidopsis by microRNA-guided mRNA degradation

Current Biology : CB

Apr 29, 2003

Zhixin XieJames C. Carrington

PMID: 12725739

DOI: 10.1016/s0960-9822(03)00281-1

Abstract

Formation of microRNA (miRNA) requires an RNaseIII domain-containing protein, termed DICER-1 in animals and DICER-LIKE1 (DCL1) in plants, to catalyze processing of an RNA precursor with a fold-back structure. Loss-of-function dcl1 mutants of Arabidopsis have low levels of miRNA and exhi...read more

Mentioned in this Paper

Mutant
Oligonucleotide Primers
Arabidopsis
HC-Pro
Feedback, Biochemical
260

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Paper Details
References
  • References19
  • Citations252
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