Negative Reactant Ion Formation in High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS)

Journal of the American Society for Mass Spectrometry
Maria AllersStefan Zimmermann

Abstract

Due to the operation at background pressures between 10 - 40 mbar and high reduced electric field strengths of up to 120 Td, the ion-molecule reactions in High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) differ from those in classical ambient pressure IMS. In the positive ion polarity mode, the reactant ions H+(H2O)n, O2+(H2O)n and NO+(H2O)n are observed in the HiKE-IMS. The relative abundances of these reactant ion species significantly depend on the reduced electric field strength in the reaction region, the operating pressure, and water concentration in the reaction region. In this work, the formation of negative reactant ions in HiKE-IMS is investigated in detail. Based on kinetic and thermodynamic data from literature, the processes resulting in the formation of negative reactant ions are kinetically modeled. To verify the model, we present measurements of the negative reactant ion population in the HiKE-IMS and its dependence on the reduced electric field strength as well as the water and carbon dioxide concentration in the reaction region. The ion species underlying individual peaks in the ion mobility spectrum are identified by coupling the HiKE-IMS to a time-of-flight mass spectrometer (TOF-MS) using a simple ...Continue Reading

References

Nov 16, 2006·Analytical Chemistry·Erkinjon G NazarovGary A Eiceman
Jan 3, 2015·The Review of Scientific Instruments·P CochemsS Zimmermann
Apr 3, 2020·Journal of the American Society for Mass Spectrometry·Maria AllersStefan Zimmermann
May 7, 2020·Journal of the American Society for Mass Spectrometry·Maria AllersStefan Zimmermann

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Citations

Nov 4, 2020·Rapid Communications in Mass Spectrometry : RCM·Maria AllersStefan Zimmermann
Jan 8, 2021·Rapid Communications in Mass Spectrometry : RCM·Younes Valadbeigi, Vahideh Ilbeigi
Jul 2, 2021·Analytical Chemistry·Juha-Pekka HietaRisto Kostiainen
Sep 3, 2020·Journal of the American Society for Mass Spectrometry·Christoph SchaeferStefan Zimmermann

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