Negative Tuberculin Skin Test and Prediction of Reversion of QuantiFERON Interferon Gamma Release Assay in US Healthcare Workers

Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
Wendy ThanassiJerome Yesavage

Abstract

QuantiFERON tuberculosis tests (QFT) reverted in (612) 77% of 1,094 low-risk healthcare workers (HCW) testing less than 1.16 IU/mL. Of HCW testing greater than 1.1 IU/mL, 33 (59%) of 56 with negative tuberculin skin tests (TST) reverted vs 8 (6%) of 125 with positive TSTs. Retesting low-risk QFT-positive and TST-negative HCW is prudent.

References

Apr 3, 2004·American Journal of Respiratory and Critical Care Medicine·Toru MoriIzuo Tsuyuguchi
Sep 13, 2012·PloS One·William C WhitworthGerald H Mazurek
Oct 30, 2012·American Journal of Respiratory and Critical Care Medicine·John Z MetcalfeEdward A Graviss
Jul 28, 2013·Journal of Occupational and Environmental Medicine·Amy BehrmanUNKNOWN ACOEM Medical Center Occupational Health Section Task Force on Tuberculosis and Health Care Workers

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Citations

Jul 9, 2016·Annals of the American Thoracic Society·Wendy T Thanassi, William G Buchta
Nov 3, 2017·PloS One·Jerker JonssonThomas Schön

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