Neglect, HPA axis reactivity, and development

International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience
Emily B Reilly, Megan R Gunnar

Abstract

Neglect is a common and frequently chronic form of child maltreatment that can compromise child development and increase the risk of physical and psychological problems. In this review, we discuss one of the potential ways neglect becomes biologically embedded by shaping the development of a key stress responsive system: namely, the hypothalamic-pituitary-adrenal (HPA) axis. Several potential mediators and moderators of this process are examined, including inflammation, attachment and social buffering, self-regulation, child sex and age, and genetics.

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Citations

Sep 29, 2020·Frontiers in Bioengineering and Biotechnology·Cheyenne Samson, Ahyeon Koh
Jan 2, 2021·Psychoneuroendocrinology·Haley M AppelmannPeggy M Zoccola

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