Neoadjuvant chemotherapy for operable breast cancer: individualizing locoregional and systemic therapy

Surgical Oncology Clinics of North America
Harry D Bear

Abstract

Neoadjuvant chemotherapy (NAC) is being used with increasing frequency in the multidisciplinary care of women with breast cancer. NAC can increase the chances for successful breast conservation and may decrease the need for axillary node dissection in selected patients. Some patients with chemoresistant tumors may benefit more from hormonal neoadjuvant therapy. The greatest potential for this approach is to predict responses of different breast cancers to therapy based on molecular profiles. This will accelerate better understanding of breast cancer biology and progress toward improved and more individualized therapy.

References

Jul 1, 1997·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·B FisherN V Dimitrov
Aug 15, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·B FisherH D Bear
Oct 1, 1998·The New England Journal of Medicine·D KragP Beitsch
Mar 18, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·H M KuererS E Singletary
Jul 13, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·K M McMastersM J Edwards
Mar 16, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ian C SmithKeith N Ogston
Oct 17, 2002·Journal of the National Cancer Institute·Bruce Goldman
Aug 9, 2003·The New England Journal of Medicine·Umberto VeronesiRoberto Gennari
Oct 16, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Harry D BearUNKNOWN National Surgical Adjuvant Breast and Bowel Project Protocol B-27
Jan 30, 2004·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·M-C MathieuM Spielmann
Mar 6, 2004·Breast Cancer Research and Treatment·Laura MartincichMassimo Aglietta
Oct 12, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Marco ColleoniAron Goldhirsch
Dec 31, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Massimo CristofanilliGabriel N Hortobagyi
Jan 11, 2005·Cancer·Allen M ChenThomas A Buchholz
Jan 22, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Kyoko Iwao-KoizumiKikuya Kato
Feb 3, 2005·Journal of the National Cancer Institute·Davide MauriJohn P A Ioannidis
Apr 20, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Eleftherios P MamounasNorman Wolmark
Jun 2, 2005·Journal of the National Cancer Institute·Sanjay Popat, Ian E Smith
Sep 8, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Luca GianniSteven Shak
Sep 15, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Gary H LymanUNKNOWN American Society of Clinical Oncology
Sep 17, 2005·American Journal of Surgery·Julie L JonesBarbara L Smith
Nov 19, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Roman RouzierGabriel N Hortobagyi
Dec 20, 2005·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Luca GianniUNKNOWN European Cooperative Trial in Operable Breast Cancer Study Group
Dec 20, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Bryan T HennessyVicente Valero
Mar 1, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Valentina GuarneriAna M Gonzalez-Angulo
Apr 12, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Harry D BearNorman Wolmark
Nov 14, 2006·Magnetic Resonance Imaging Clinics of North America·Nola Hylton
Jan 18, 2007·Journal of the National Cancer Institute·Mitch DowsettUNKNOWN IMPACT Trialists Group

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Citations

Jan 1, 2012·Expert Opinion on Medical Diagnostics·Kenneth Ph Pritzker, Laura B Pritzker
Mar 8, 2013·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M V Schaverien, D A Munnoch
Aug 12, 2019·Breast Cancer Research and Treatment·Ashley C PariserSarah S Mougalian

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