Neoadjuvant use of ipilimumab in locally advanced melanoma

Journal of Surgical Oncology
Lynn J HowieApril K S Salama

Abstract

Recent advances in immune modulating therapies show great promise for patients with advanced melanoma, however optimal strategies for achieving long-term disease control in locally advanced melanoma are unclear. We present two cases of neoadjuvant ipilimumab, one case in combination with isolated limb infusion (ILI) followed by surgical resection and one followed by surgery alone. Both patients have had durable responses. These cases highlight the ongoing need for prospective trials in the neoadjuvant setting.

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Citations

Nov 28, 2018·Journal of Surgical Oncology·Minyoung KwakGeorgia M Beasley
Mar 1, 2017·Melanoma Management·Richard TyrellGary B Deutsch
Jul 25, 2018·American Journal of Clinical Dermatology·Meredith A McKean, Rodabe N Amaria
Feb 11, 2021·Biomedicines·Jüri TerasHidde M Kroon

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