Neodymium:yttrium-aluminum-garnet capsulotomy and intraocular pressure in pseudophakic patients with glaucoma

Ophthalmology
Eric A BarnesMichael Behrend

Abstract

To determine the 1- and 3-hour changes in intraocular pressure after neodymium:yttrium-aluminum-garnet (Nd:YAG) capsulotomy in pseudophakic patients with glaucoma and to determine the effect of acetazolamide and apraclonidine on these changes. Randomized controlled trial. Pseudophakic patients with glaucoma requiring Nd:YAG posterior capsulotomy (n = 76). Patients undergoing Nd:YAG posterior capsulotomy were randomly allocated to receive no therapy, oral acetazolamide (250 mg), or topical apraclonidine 1% within 1 hour before capsulotomy. Intraocular pressures 1 and 3 hours after laser therapy were recorded. Data were available for 76 eyes in 76 patients. Twenty-nine patients received no therapy; 24, oral acetazolamide; and 23, apraclonidine. One fifth (6/29) of patients with glaucoma developed a pressure rise of > or =5 mmHg if untreated, and 3% (1/29) developed a pressure rise of >10 mmHg. In comparison, no patients in the acetazolamide group developed a pressure rise of > or =5 mmHg (P = 0.02), and 1 of 24 in the apraclonidine group (P = 0.08) developed such a pressure rise, with none developing a pressure rise of >10 mmHg. When comparing all treated with nontreated, a reduction in the proportion with pressure rise was found...Continue Reading

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Citations

Feb 3, 2005·Photomedicine and Laser Surgery
Mar 23, 2005·Photomedicine and Laser Surgery
Apr 29, 2008·American Journal of Ophthalmology·Eva StifterAlexandra Luksch
May 26, 2015·Journal of Ophthalmic & Vision Research·Rahul BhargavaKulbhushan Prakash Chaudhary
Oct 1, 2011·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Tarek M Eid
Feb 24, 2017·BMC Ophthalmology·Andreas DiagourtasDimitrios Papaconstantinou

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