Nov 17, 2019

Neonatal care bundles are associated with a reduction in the incidence of intraventricular haemorrhage in preterm infants: a multicentre cohort study

Archives of Disease in Childhood. Fetal and Neonatal Edition
Karen A de Bijl-MarcusGerda van Wezel-Meijler


To investigate the effect of a nursing intervention bundle, applied during the first 72 hours of life, on the incidence of germinal matrix-intraventricular haemorrhage (GMH-IVH) in very preterm infants. Multicentre cohort study. Two Dutch tertiary neonatal intensive care units. The intervention group consisted of 281 neonates, whereas 280 infants served as historical controls (gestational age for both groups <30 weeks). After a training period, the nursing intervention bundle was implemented and applied during the first 72 hours after birth. The bundle consisted of maintaining the head in the midline, tilting the head of the incubator and avoidance of flushing/rapid withdrawal of blood and sudden elevation of the legs. The incidence of GMH-IVH occurring and/or increasing after the first ultrasound (but within 72 hours), cystic periventricular leukomalacia and/or in-hospital death was the primary composite outcome measure. Logistic regression analysis was used to explore differences between groups. The nursing intervention bundle was associated with a lower risk of developing a GMH-IVH (any degree), cystic periventricular leukomalacia and/or mortality (adjusted OR 0.42, 95% CI 0.27 to 0.65). In the group receiving the bundle, al...Continue Reading

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Mentioned in this Paper

Midline (Qualifier Value)
Ventricular Hemorrhage
Cessation of Life
Neonatal Intensive Care
Nursing Interventions
Multicenter Hemophilia Cohort Study

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