PMID: 9529467Apr 8, 1998Paper

Neonatal circumcision. Randomized trial of a sucrose pacifier for pain control

Archives of Pediatrics & Adolescent Medicine
M HerschelR Mittendorf

Abstract

To assess the effectiveness of oral sucrose via a nipple compared with no treatment and dorsal penile nerve block (DPNB) for alleviating pain in neonatal circumcision. Randomized control trial. Data analysis performed by investigators blinded to the 3 treatment groups. University teaching hospital, General Care Nursery. One hundred nineteen full-term male, normal birth weight neonates, 12 hours old or older. No treatment (our standard care), DPNB, or oral sucrose prior to circumcision. Differences between groups in heart rate and oxygen saturation changes from baseline during specified intervals of the circumcision procedure. Differences between groups in loss of data due to episodes of excessive motion. Sucrose gave significant (P < .001) pain relief compared with the no treatment control throughout most of the circumcision and particularly in the early stages of the procedure. Overall, the average difference in the elevation of heart rates during the circumcision operative procedure among the 3 groups and the 95% confidence intervals (CIs) were as follows: control vs DPNB, 27.1 beats/min (17.6, 36.6) and control vs sucrose, 9.7 beats/min (0.1, 19.3). Furthermore, newborns who received either DPNB or sucrose had less loss of o...Continue Reading

Citations

Jul 31, 2002·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Janet GeyerJerome Yankowitz
Oct 29, 2008·Evidence-based Complementary and Alternative Medicine : ECAM·Jennie C I TsaoLonnie K Zeltzer
Dec 22, 2010·Japan Journal of Nursing Science : JJNS·Takahiro Kakeda
Jun 3, 2004·Best Practice & Research. Clinical Anaesthesiology·Martin Jöhr, Thomas M Berger
Aug 18, 2006·Neonatal Network : NN·Jesse W Ford
Mar 28, 2001·Paediatric Drugs·A Taddio
Oct 21, 2004·The Cochrane Database of Systematic Reviews·B Brady-FryerJ A Lander
Feb 24, 2001·Obstetrical & Gynecological Survey·R S Litman
Jul 16, 2016·The Cochrane Database of Systematic Reviews·Bonnie StevensAllyson Shorkey
Jul 29, 2003·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Nancy L Kraft
Apr 22, 2016·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Marie Pier DesjardinsSerge Gouin
Nov 24, 1999·Pain·E M Blass, L B Watt
Sep 23, 2003·MCN. the American Journal of Maternal Child Nursing·Margaret MalnoryRussell S Kirby
Apr 26, 2006·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Alexander J RogersHarold K Simon
Oct 11, 2020·Journal of Pediatric Urology·Muhieddine LabbanAhmad Zaghal
Aug 29, 2012·Pediatrics·UNKNOWN American Academy of Pediatrics Task Force on Circumcision
Jan 5, 2000·Pediatrics·L GrayE M Blass
Apr 3, 2002·Pediatrics·Larry GrayElliott M Blass

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