Neonatal Endocrinologic Problems in Collodion Babies

Pediatric Dermatology
Ahmet OzdemirMehmet Adnan Ozturk

Abstract

To identify endocrinologic problems, particularly those concerning growth, in collodion babies (CBs). Clinically identified newborn CBs were included in the study group (group 1). Because CBs are generally born premature, small for gestational age (SGA), or both, a control group matched to the study group in terms of gestational age and birthweight (group 2) was also established. Blood specimens were collected from both groups for thyroid function tests and to measure serum growth hormone (GH), insulinlike growth factor 1 (IGF-1) and IGF binding protein-3 (IGFBP-3) levels. Group 1 consisted of 42 CBs (25 male, 17 female) with gestational ages of 32 to 42 weeks and birthweights of 1,400 to 4,000 g. Twelve were assessed as premature and 17 as SGA. Serum IGF-1 and IGFBP-3 levels were lower and serum GH levels higher than in controls. Primary hypothyroidism was diagnosed in 10 patients in the study group, subclinical hypothyroidism in 2, and central hypothyroidism in 1. A statistically significant difference was determined between the groups in terms of primary hypothyroidism (p = 0.01). Serum GH levels were weakly negatively correlated with birthweight (correlation coefficient [r] = -0.32, p = 0.04) and serum IGF-1 (r = -0.38, p =...Continue Reading

References

Sep 1, 1992·American Journal of Medical Genetics·R SiebnerJ Sack
Apr 1, 1991·European Journal of Pediatrics·J P ChanoineF Delange
Jun 1, 1986·Archives of Disease in Childhood·J S BamforthR John
Oct 13, 1998·The Journal of Clinical Endocrinology and Metabolism·A L Ogilvy-StuartD B Dunger
Jan 30, 2003·American Journal of Clinical Dermatology·John J DiGiovanna, Leslie Robinson-Bostom
Jan 22, 2004·Journal of Pediatric Gastroenterology and Nutrition·Ashley J FowlerMelvin B Heyman
Sep 11, 2008·Journal of Pediatric Endocrinology & Metabolism : JPEM·Selim KurtogluNihal Hatipoglu
Oct 18, 2012·Oman Medical Journal·Zahra RazaviSaadat Torabian
Nov 30, 2012·Molecular Biology Reports·Nacim LouhichiFaiza Fakhfakh
Jan 30, 2013·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Dilek SariciAbdulkerim Gokoglu
Feb 19, 2013·Orphanet Journal of Rare Diseases·Hélène DufresneCharles Taïeb
Jun 13, 2015·Journal of Endocrinological Investigation·S Kurtoğlu, N Hatipoglu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.