Abstract
In a health maintenance organization population, we determined the incidence of early-onset (at less than or equal to 7 days) neonatal group B streptococcal (GBS) disease, the sensitivity and prevalence of labor risk factors, the adherence to a protocol for intrapartum antibiotics, and the costs for care of and outcomes of affected infants. Mothers and infants at four health maintenance organization hospitals in northern California in 1989 to 1995 were studied retrospectively using computerized databases and chart review. In 1994, two of the four hospitals had adopted protocols similar to the ACOG recommendations for intrapartum antibiotics for women with labor risk factors (preterm, temperature 100.4F or higher, or rupture of membranes (ROM) 18 hours or more). Among the 79,940 live births, the incidence of early-onset neonatal GBS infection was higher among preterm than among term infants (3.1 compared with 0.9 per 1000). Before protocol adoption, 68% of 65 infants with GBS had mothers with labor risk factors. Approximately 18% of all mothers had labor risk factors: 7.7% had preterm delivery, and 10.6% had term delivery with fever and/or ROM 18 hours or more. At the two hospitals that adopted GBS protocols, GBS incidence was r...Continue Reading
References
May 1, 1992·American Journal of Public Health·N Krieger
Sep 1, 1990·The Journal of Infectious Diseases·A SchuchatC V Broome
Jul 1, 1994·The Pediatric Infectious Disease Journal·A SchuchatJ D Wenger
Apr 1, 1994·Obstetrics and Gynecology·R S GibbsR L Sweet
Aug 1, 1995·The Pediatric Infectious Disease Journal·H S JafariJ D Wenger
Jan 1, 1997·Obstetrics and Gynecology·C G WhitneyA Schuchat
Dec 1, 1996·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·J W Coleman
Jun 1, 1997·Pediatrics·S P Gotoff, K M Boyer
Nov 26, 2002·Paediatric and Perinatal Epidemiology·Monique Trijbels-SmeuldersLouis A A Kollée
Citations
Jun 30, 2001·Obstetrics and Gynecology·J P WattJ Schulkin
Feb 19, 1999·Lancet·A Schuchat
Jan 3, 2001·European Journal of Obstetrics, Gynecology, and Reproductive Biology·J L VoluménieR Frydman
Aug 21, 2001·BJOG : an International Journal of Obstetrics and Gynaecology·C M StanO Irion
Apr 8, 2003·The Lancet Infectious Diseases·Matthew R MooreAnne Schuchat
Jul 26, 2002·The New England Journal of Medicine·Stephanie J SchragUNKNOWN Active Bacterial Core Surveillance Team
Feb 22, 2011·Journal of Tropical Pediatrics·Mohamed Abdelmaaboud, Abdelbaset Fakhry Mohammed
Dec 1, 2001·MCN. the American Journal of Maternal Child Nursing·L ChandranP P Lincoln
Apr 14, 2000·Current Opinion in Pediatrics·S P Gotoff
Feb 22, 2013·Israel Journal of Health Policy Research·Gary M GinsbergYoram Lotan
Aug 7, 2009·Journal of Perinatology : Official Journal of the California Perinatal Association·R J PowersUNKNOWN Perinatal Quality Improvement Panel of the California Perinatal Quality Care Collaborative
Jan 5, 2008·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Sudqi HamadaPrakesh S Shah
Nov 29, 2001·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·D C James
Feb 24, 2006·BJOG : an International Journal of Obstetrics and Gynaecology·E de MirandaF R Rosendaal
Jan 7, 2010·Infectious Diseases in Obstetrics and Gynecology·Mark A TurrentineJoan M Mastrobattista
Jul 8, 2016·Expert Review of Vaccines·Anna L Kenchington, Ronald F Lamont
Jun 28, 2000·American Journal of Obstetrics and Gynecology·D P ReisnerD A Luthy
Aug 5, 2000·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·S J SchragA Schuchat
May 30, 2003·Journal of Perinatology : Official Journal of the California Perinatal Association·Laura RileyEllice Lieberman
Oct 9, 2002·Journal of Perinatology : Official Journal of the California Perinatal Association·Conrad J Clemens, E Kaye Gable
Oct 9, 2002·Journal of Perinatology : Official Journal of the California Perinatal Association·Imelda P UyRonnie Guillet
Dec 21, 2006·Maternal and Child Health Journal·Louisa CastrodaleThomas Hennessy
Jul 1, 2002·Paediatrics & Child Health·H Dele Davies
Aug 2, 2000·Pediatrics·P BrombergerD B Petitti
Aug 2, 2000·Pediatrics·G J EscobarR Bergen
Apr 2, 1999·Pediatrics·J C Mohle-BoetaniG Escobar
Jun 3, 1999·Pediatrics·W E BenitzM L Druzin
Jun 3, 1999·Pediatrics·W E BenitzM L Druzin