PMID: 9189840Jan 1, 1997Paper

Neonatal outcome in women treated for the antiphospholipid syndrome during pregnancy

Journal of Perinatal Medicine
F BotetJ Balasch

Abstract

The aim of this study was to determine the neonatal outcome in women with well-characterized antiphospholipid syndrome treated during pregnancy with low-dose aspirin. We compared 38 babies born after 36 pregnancies of 33 women diagnosed as having antiphospholipid syndrome with a group of 38 control infants matched for the same gestational age at birth. In all 76 newborns we studied the maternal events associated with the antiphospholipid syndrome, mothers' treatment and neonatal data. All mothers with antiphospholipid syndrome were treated with low-dense aspirin. Prednisone was only prescribed due to maternal complications and heparin in a case of thrombosis. No significant relation was found between maternal treatment and neonatal complications. The prematurity rate in these newborns was high 14% and the neonatal mortality (5.8%) was only associated with extreme prematurity (p < 0.001). In our population the overall rate of neonatal complications was higher than in the general population, but when compared with a similar group of newborns no significant differences were found. Our results suggest that primary antiphospholipid syndrome appears to be improved by low-dose aspirin treatment, with a high rate of neonatal survival (...Continue Reading

References

Jan 1, 1992·Autoimmunity·A PassalevaR Abbate
Nov 1, 1992·Clinical and Experimental Immunology·P FishmanY Shoenfeld
Jun 1, 1992·Clinical Obstetrics and Gynecology·J T RepkeP W Kaplan
Jun 1, 1989·American Journal of Reproductive Immunology : AJRI·D A Triplett
Nov 1, 1993·American Journal of Clinical Pathology·R L Bick
May 1, 1993·American Journal of Reproductive Immunology : AJRI·R Shurtz-SwirskiY Shoenfeld

❮ Previous
Next ❯

Citations

Apr 14, 2005·Best Practice & Research. Clinical Endocrinology & Metabolism·Lorin Lakasing, Catherine Williamson
Sep 30, 1999·Journal of Perinatal Medicine·J A BrewsterR G Farquharson
Jan 28, 2009·Current Rheumatology Reports·Angela TincaniMario Motta
Sep 22, 2009·Early Human Development·Mario MottaGaetano Chirico
Aug 2, 2006·Rheumatic Diseases Clinics of North America·Rolando Cimaz, Elodie Descloux
Sep 6, 2001·Rheumatic Diseases Clinics of North America·H A ShehataM A Khamashta
Jan 23, 1998·Journal of Women's Health
Apr 21, 2007·Pediatrics International : Official Journal of the Japan Pediatric Society·Tomoko UsugiMakiko Osawa
Jan 30, 2004·American Journal of Reproductive Immunology : AJRI·Shelly Tartakover MatalonAsher Ornoy
Mar 4, 2020·Current Rheumatology Reports·Arzu Soybilgic, Tadej Avcin

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.