Neonatal staphylococcal scalded skin syndrome: clinical and outbreak containment review.

European Journal of Pediatrics
Orla NeylonRoy K Philip

Abstract

Staphylococcal scalded skin syndrome (SSSS) is a toxin-mediated exfoliating skin condition predominated by desquamation and blistering. Neonatal outbreaks have already been reported; however, our outbreak highlights the potential for SSSS following neonatal health promotion measures such as intra-muscular vitamin K administration and metabolic screening (heel prick) as well as effective case containment measures and the value of staff screening. Between February and June 2007, five confirmed cases of neonatal SSSS were identified in full-term neonates born in an Irish regional maternity hospital. All infants were treated successfully. Analysis of contact and environmental screening was undertaken, including family members and healthcare workers. Molecular typing on isolates was carried out. An outbreak control team (OCT) was assembled and took successful prospective steps to prevent further cases. All five Staphylococcus aureus isolates tested positive for exfoliative toxin A, of which two distinct strains were identified on pulsed-field gel electrophoresis analysis. Two cases followed staphylococcal inoculation during preventive measures such as intra-muscular vitamin K administration and metabolic screening (heel prick). None...Continue Reading

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Citations

Jan 1, 2011·BMJ Case Reports·Roberta OnesimoCarlo Fundarò
Sep 17, 2013·Pediatric Dermatology·Inbal BraunsteinJames R Treat
May 11, 2019·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·D HuggardR K Philip
Dec 10, 2015·São Paulo Medical Journal = Revista Paulista De Medicina·Andreas HörnerCláudia Giacomolli
Dec 8, 2020·Pediatric Dermatology·Carmen Liy-WongIrene Lara-Corrales

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