Neonatal thrombocytopenia

Seminars in Thrombosis and Hemostasis
D George, J B Bussel

Abstract

The workup and management of neonatal thrombocytopenia is a problem commonly encountered by pediatric hematologists and neonatologists. The incidence of this problem has been estimated to range as high as 1% or more for healthy term infants to 20% of newborns admitted to a neonatal intensive care unit. An expeditious approach to this problem and timely intervention when necessary can prevent or attenuate the potentially serious consequences of this problem, most notably that of intracranial hemorrhage. In this article we discuss the incidence and causes of this problem, and present an algorithm for an approach to the neonate with thrombocytopenia. This will include consideration of fetal thrombocytopenia and its management, that is, in repeated pregnancies in women with alloimmune thrombocytopenia. Case discussions will be used to illustrate the algorithm.

Citations

Mar 11, 2000·Obstetrics and Gynecology·S SainioR Kekomäki
Dec 12, 2003·European Journal of Haematology·Matthew A SaxonhouseMartha C Sola
Nov 21, 1997·Journal of the American Academy of Dermatology·E BaselgaN B Esterly
Apr 25, 2008·Blood Reviews·Irene RobertsNeil A Murray
May 20, 2000·American Journal of Obstetrics and Gynecology·R M SilverJ R Scott
Feb 20, 2003·Neurosurgery·Balraj S JhawarRolando F Del Maestro
Feb 16, 2000·Pediatric Research·S J Israels
Nov 2, 2014·American Journal of Physiology. Heart and Circulatory Physiology·Mudit KulshresthaDonald E Mager
Jul 27, 2002·Journal of Pediatric Hematology/oncology·Oya Levendoglu-TugalSomasundaram Jayabose
Dec 13, 2002·Acta Paediatrica. Supplement·N A Murray
Dec 13, 2002·Acta Paediatrica. Supplement·M C Sola, L M Rimsza
Sep 15, 2000·Clinics in Perinatology·M C SolaL M Rimsza

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