Neonatal thyrotropin (TSH) screening as a tool for monitoring iodine nutrition in Armenia.

European Journal of Clinical Nutrition
Nicholas HutchingsJohn P Bilezikian

Abstract

Neonatal thyrotropin (TSH) is influenced not only by the infant's own thyroid function, but also by maternal thyroid status, and can thus provide a general index of thyroid health in the community. In 2012, the Republic of Armenia implemented a program of universal neonatal hypothyroidism screening by means of measuring the serum TSH level. The Arabkir Medical Center in Yerevan, Armenia, has maintained records of neonatal TSH screening data comprising nearly 100% of all births in Armenia from 2012 through 2016. We analyzed these data to determine the frequency of neonatal TSH levels higher than the cut point of 5 mIU/L, indicative of sufficient iodine nutrition status, and to detect any time dependence over years or regional variation. A total of 127,177 records from 2012 to 2016 were included. The geographic distribution of neonatal TSH records was reflective of the population of Armenia; the national percentage of records over 5 mIU/L ranged from a high of 2.88% in 2012 to a low of 1.71% in 2016. Minimal regional variation was noted, from a 2012-2016 cumulative high of 2.93% of records over 5 mIU/L in Shirak province to a low of 0.95% in the Vayots Dzor province. From all years and from all regions, values were consistently a...Continue Reading

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Dec 12, 2013·Journal of General Internal Medicine·Rachel D A HavyerDarcy A Reed
Sep 8, 2018·Public Health Nutrition·Nicholas HutchingsJohn P Bilezikian

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Citations

Jun 7, 2019·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Nicholas HutchingsJohn P Bilezikian

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